ArticleJournal of virological methods2019
Analytical evaluation of the microarray-based FluChip-8G Influenza A+B Assay.
Article in Journal of virological methods, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Article
- An evaluation of the InDevR FluChip-8G insight microarray assay in characterizing influenza a viruses.Tropical diseases, travel medicine and vaccines · 2021Article
- Clinical validation of the FluChip-8G Influenza A+B Assay for influenza type and subtype identification.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2019Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
backgroundInfluenza causes a significant annual disease burden, with characterization of the infecting virus important in clinical and public health settings. Rapid immunoassays are fast but insensitive, whereas real-time RT-PCR is sensitive but susceptible to genetic mutations and often requires multiple serial assays. The FluChip-8G Influenza A+B Assay provides type and subtype/lineage identification of influenza A and B, including non-seasonal A viruses, in a single microarray-based assay with same day turnaround time.
objectiveTo evaluate key analytical performance characteristics of the FluChip-8G Influenza A+B Assay. STUDY
designAnalytical sensitivity, cross-reactivity, and multi-site reproducibility were evaluated.
resultsThe limit of detection (LOD) for the FluChip-8G influenza A+B Assay ranged from 5.8 × 10
conclusionThe FluChip-8G Influenza A+B Assay is an effective new method for detecting and identifying both seasonal and non-seasonal influenza viruses, as revealed by good sensitivity and robust reactivity to 52 unique strains of influenza virus. In addition, the lack of cross-reactivity to non-influenza pathogens and high lab-to-lab reproducibility highlight the analytical performance of the assay as an alternative to real-time RT-PCR and sequencing-based assays. Clinical validation of the technology in a multi-site clinical study is the subject of a separate investigation.
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Registered trials
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