Evidence map›Paper›PMID 31271702›Full record

ArticleMycoses2019

ECMM CandiReg-A ready to use platform for outbreaks and epidemiological studies.

Philipp Koehler, Maiken Cavling Arendrup, Sevtap Arikan-Akdagli, Matteo Bassetti, Stéphane Bretagne, Lena Klingspor, Katrien Lagrou, Jacques F Meis, Riina Rautemaa-Richardson, Silke Schelenz and 27 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Mycoses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Design and set-up of the leptospirosis registryFrontiers in public health · 2025
    Article
  3. Article
  4. Current issues in molecular biology · 2024
    Review
  5. Article
  6. Article
  7. Observational
  8. Review
  9. Review
  10. Increasing Number of Cases Due toJournal of clinical medicine · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Philipp KoehlerFaculty of Medicine, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf (CIO ABCD), Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-7386-7495
Maiken Cavling ArendrupUnit of Mycology, Statens Serum Institute, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-4747-0144
Sevtap Arikan-AkdagliDepartment of Medical Microbiology, Hacettepe University School of Medicine, Ankara, Turkey.ORCID https://orcid.org/0000-0001-9807-6764
Matteo BassettiDepartment of Medicine, Infectious Diseases Clinic, University of Udine and Azienda Sanitaria Universitaria Integrata di Udine, Udine, Italy.ORCID https://orcid.org/0000-0002-2004-3724
Stéphane BretagneParasitology-Mycology Laboratory, Lariboisière Saint-Louis Fernand Widal Hospitals, Assistance Publique-Hôpitaux de Paris (APHP), Molecular Mycology Unit, CNRS, UMR2000, Institut Pasteur, Université de Paris, Paris, France.ORCID https://orcid.org/0000-0001-6870-3800
Lena KlingsporDepartment of Laboratory Medicine, Clinical Microbiology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-8259-3556
Katrien LagrouLaboratory of Clinical Bacteriology and Mycology, Department of Microbiology, Immunology and Transplantation, Excellence Center for Medical Mycology (ECMM), KU Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0001-8668-1350
Jacques F MeisDepartment of Medical Microbiology and Infectious Diseases, Excellence Center for Medical Mycology (ECMM), Center of Expertise in Mycology Radboudumc/CWZ, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0003-3253-6080
Riina Rautemaa-RichardsonDepartment of Infectious Diseases and Mycology Reference Centre Manchester, Manchester University NHS Foundation Trust, Manchester, UK.ORCID https://orcid.org/0000-0002-1071-6040
Silke SchelenzDepartment of Microbiology, Royal Brompton Hospital, London, UK.ORCID https://orcid.org/0000-0002-0108-4619
Axel HamprechtInstitute for Medical Microbiology, Immunology and Hygiene, University Hospital of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0003-1449-5780
Felix C KoehlerCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Oliver KurzaiNational Reference Center for Invasive Fungal Infections, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute, Jena, Germany.
Jon Salmanton-GarcíaFaculty of Medicine, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf (CIO ABCD), Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-6766-8297
Jörg-Janne VehreschildFaculty of Medicine, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf (CIO ABCD), Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-5446-7170
Alexandre AlanioParasitology-Mycology Laboratory, Lariboisière Saint-Louis Fernand Widal Hospitals, Assistance Publique-Hôpitaux de Paris (APHP), Molecular Mycology Unit, CNRS, UMR2000, Institut Pasteur, Université de Paris, Paris, France.ORCID https://orcid.org/0000-0001-9726-3082
Ana Alastruey-IzquierdoNational Centre for Micobiology, Instituto de Salud Carlos III, Madrid, Spain.ORCID https://orcid.org/0000-0001-8651-4405
Valentina Arsic ArsenijevicNational Reference Medical Mycology Laboratory, Faculty of Medicine, Institute of Microbiology and Immunology, University of Belgrade, Belgrade, Serbia.ORCID https://orcid.org/0000-0001-8132-3300
Jean-Pierre GangneuxInstitut de Recherche en Santé, Environnement et travail, Inserm, CHU de Rennes, EHESP, UMR_S 1085, Université de Rennes, Rennes, France.
Neil A R GowSchool of Biosciences, University of Exeter, Exeter, UK.ORCID https://orcid.org/0000-0002-2776-5850
Suzana HadinaDepartment of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia.
Petr HamalDepartment of Microbiology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czechia.ORCID https://orcid.org/0000-0002-5361-8125
Elizabeth JohnsonPublic Health England Mycology Reference Laboratory, National Infection Services, PHE South West Laboratory, Science Quarter, Southmead Hospital, Southmead, Bristol, UK.
Nikolay KlimkoDepartment of Clinical Mycology, Allergy and Immunology, North Western State Medical University, Saint Petersburg, Russia.ORCID https://orcid.org/0000-0001-6095-7531
Cornelia Lass-FlörlDivision of Hygiene and Medical Microbiology, Excellence Center for Medical Mycology (ECMM), Medical University of Innsbruck, Innsbruck, Austria.ORCID https://orcid.org/0000-0002-2946-7785
Mihai MaresLaboratory of Antimicrobial Chemotherapy, Ion Ionescu de la Brad University, Iași, Romania.ORCID https://orcid.org/0000-0002-3103-4954
Volkan ÖzenciDepartment of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-8069-4027
Tamas PappMTA-SZTE Fungal Pathogenicity Mechanisms Research Group, Department of Microbiology, University of Szeged, Szeged, Hungary.ORCID https://orcid.org/0000-0001-8211-5431
Emmanuel RoilidesInfectious Diseases Unit, 3rd Department of Pediatrics, Faculty of Medicine, Hippokration General Hospital, Aristotle University School of Health Sciences, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-0202-364X
Raquel SabinoDepartment of Infectious Diseases, Nacional Institute of Health Dr. Ricardo Jorge - Reference Unit for Parasitic and Fungal Infections, Lisbon, Portugal.ORCID https://orcid.org/0000-0001-6585-7775
Esther SegalDepartment of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Alida Fe TalentoDepartment of Clinical Microbiology, Royal College of Surgeons Ireland, Dublin, Ireland.ORCID https://orcid.org/0000-0003-1271-2550
Anna Maria TortoranoDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy.ORCID https://orcid.org/0000-0003-2093-8250
Paul E VerweijDepartment of Medical Microbiology, Excellence Center for Medical Mycology (ECMM), Center of Expertise in Mycology Radboudumc/CWZ, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0002-8600-9860
Martin HoeniglSection of Infectious Diseases and Tropical Medicine, Medical University of Graz, Graz, Austria.ORCID https://orcid.org/0000-0002-1653-2824
Oliver A CornelyFaculty of Medicine, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf (CIO ABCD), Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0001-9599-3137
European Confederation of Medical Mycology (ECMM)

Funding

Medical Research Council MR/N006364/1Wellcome Trust 101873
6 · The paper itself

Abstract

backgroundRecent outbreaks of Candida auris further exemplify that invasive Candida infections are a substantial threat to patients and healthcare systems. Even short treatment delays are associated with higher mortality rates. Epidemiological shifts towards more resistant Candida spp. require careful surveillance.

objectivesTriggered by the emergence of C auris and by increasing antifungal resistance rates the European Confederation of Medical Mycology developed an international Candida Registry (FungiScope™ CandiReg) to allow contemporary multinational surveillance.

methodsCandiReg serves as platform for international cooperation to enhance research regarding invasive Candida infections. CandiReg uses the General Data Protection Regulation compliant data platform ClinicalSurveys.net that holds the electronic case report forms (eCRF). Data entry is supported via an interactive macro created by the software that can be accessed via any Internet browser.

resultsCandiReg provides an eCRF for invasive Candida infections that can be used for a variety of studies from cohort studies on attributable mortality to evaluations of guideline adherence, offering to the investigators of the 28 ECMM member countries the opportunity to document their cases of invasive Candida infection. CandiReg allows the monitoring of epidemiology of invasive Candida infections, including monitoring of multinational outbreaks. Here, we describe the structure and management of the CandiReg platform.

conclusionCandiReg supports the collection of clinical information and isolates to improve the knowledge on epidemiology and eventually to improve management of invasive Candida infections. CandiReg promotes international collaboration, improving the availability and quality of evidence on invasive Candida infection and contributes to improved patient management.

Indexed as

Databases, FactualDisease OutbreaksRegistriesCandidiasis, InvasiveEpidemiological MonitoringFemaleGlobal HealthHumansMaleCandidemiaepidemiologyinvasive candidiasisinvasive fungal infectionoutbreak

Identifiers

PMID31271702
PMCPMC7614793

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.