Evidence map›Paper›PMID 31271599›Full record

ArticleArquivos brasileiros de cardiologia2019

Application of Risks Scores in Acute Coronary Syndromes. How Does ProACS Hold Up Against Other Risks Scores?

Júlio Gil, Luís Abreu, Hugo Antunes, Maria Luísa Gonçalves, Maria Inês Pires, Luís Ferreira Dos Santos, Carla Henriques, Ana Matos, José Costa Cabral, Jorge Oliveira Santos

Erratum issuedAbstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Guideline for Chronic Coronary Syndrome - 2025.Arquivos brasileiros de cardiologia · 2025
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Júlio GilHospital de São Teotónio, Viseu - Portugal.ORCID 0000-0003-0277-4512
Luís AbreuHospital de São Teotónio, Viseu - Portugal.
Hugo AntunesHospital de São Teotónio, Viseu - Portugal.ORCID 0000-0002-4431-8219
Maria Luísa GonçalvesHospital de São Teotónio, Viseu - Portugal.
Maria Inês PiresHospital de São Teotónio, Viseu - Portugal.
Luís Ferreira Dos SantosHospital de São Teotónio, Viseu - Portugal.
Carla HenriquesInstituto Politécnico de Viseu e CI&DETS, Viseu - Portugal.
Ana MatosInstituto Politécnico de Viseu e CI&DETS, Viseu - Portugal.
José Costa CabralHospital de São Teotónio, Viseu - Portugal.
Jorge Oliveira SantosHospital de São Teotónio, Viseu - Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple risk scores (RS) are approved in the prediction of worse prognosis in acute coronary syndromes (ACS). Recently, the Portuguese Journal of Cardiology has proposed the ProACS RS.

objectiveApplication of several validated RS, as well as ProACS in patients, admitted for ACS. Evaluation of each RS's performance in predicting in-hospital mortality and the occurrence of all-cause mortality or non-fatal ACS at one-year follow-up and compare them to the ProACS RS.

methodsA retrospective study of ACS was performed. The following RS were applied: GRACE, ACTION Registry-GWTG, PURSUIT, TIMI, EMMACE, SRI, CHA2DS2-VASc-HS, C-ACS and ProACS. ROC Curves were created to determine the predictive power for each RS and then were directly compared to ProACS.

resultsThe ProACS, ACTION Registry-GWTG and GRACE showed a c-statistics of 0.908, 0.904 and 0.890 for predicting in-hospital mortality, respectively, performing better in ST-segment elevation myocardial infarction patients. The other RS performed satisfactorily, with c-statistics over 0.750, apart from the CHA2DS2-VASc-HS and C-ACS which underperformed. All RS underperformed in predicting worse long-term prognosis revealing c-statistics under 0.700.

conclusionProACS is an easily obtained risk score for early stratification of in-hospital mortality. When evaluating all RS, the ProACS, ACTION Registry-GWTG and GRACE RS showed the best performance, demonstrating high capability of predicting a worse prognosis. ProACS was able to demonstrate statistically significant superiority when compared to almost all RS. Thus, the ProACS has showed that it is able to combine simplicity in the calculation of the score with good performance in predicting a worse prognosis.

Indexed as

Acute Coronary SyndromeAgedAged, 80 and overFemaleHospital MortalityHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk AssessmentRisk FactorsROC Curve

Identifiers

PMID31271599
PMCPMC6684178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.