Evidence map›Paper›PMID 31271206›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2020

Pandemic Uropathogenic Fluoroquinolone-resistant Escherichia coli Have Enhanced Ability to Persist in the Gut and Cause Bacteriuria in Healthy Women.

Veronika L Tchesnokova, Elena Rechkina, Diana Chan, Helen Ghirmai Haile, Lydia Larson, Kendra Ferrier, David W Schroeder, Thalia Solyanik, Spencer Shibuya, Kelly Hansen and 4 more

Open access · greenAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Bacteriophage-mediated reduction of uropathogenicbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Comprehensive antibiotic resistome comparison ofCurrent research in microbial sciences · 2025
    Article
  10. Article
  11. A NovelAntibiotics (Basel, Switzerland) · 2024
    Article
  12. Gut residentmedRxiv : the preprint server for health sciences · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Strain belonging to an emerging, virulent sublineage of ST131Frontiers in cellular and infection microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Veronika L TchesnokovaDepartment of Microbiology, University of Washington School of Medicine.
Elena RechkinaID Genomics, Inc.
Diana ChanDepartment of Microbiology, University of Washington School of Medicine.
Helen Ghirmai HaileDepartment of Microbiology, University of Washington School of Medicine.
Lydia LarsonDepartment of Microbiology, University of Washington School of Medicine.
Kendra FerrierDepartment of Microbiology, University of Washington School of Medicine.
David W SchroederDepartment of Microbiology, University of Washington School of Medicine.
Thalia SolyanikDepartment of Microbiology, University of Washington School of Medicine.
Spencer ShibuyaDepartment of Microbiology, University of Washington School of Medicine.
Kelly HansenKaiser Permanente Washington Health Research Institute.
James D RalstonKaiser Permanente Washington Health Research Institute.
Kim RiddellKaiser Permanente Washington, Seattle.
Delia ScholesKaiser Permanente Washington Health Research Institute.
Evgeni V SokurenkoDepartment of Microbiology, University of Washington School of Medicine.
University of Washington · USKaiser Permanente · USID Genomics (United States) · USKaiser Permanente Washington Health Research Institute · US

Funding

Molecular Clonality of Uropathogenic E. ColiR01AI106007 · NIAID · UNIVERSITY OF WASHINGTON · PI SOKURENKO, EVGENI VENIAMINOVIC · 2014 to 2024
$7.5M
Clonotyping Technology for Prediction of Antibiotic ResistanceR42AI116114 · NIAID · IDGENOMICS, INC. · PI SOKURENKO, EVGENI VENIAMINOVIC, ZUCKERMAN, LINDA · 2016 to 2018
$3.0M
Clonotyping Technology for Prediction of Antibiotic ResistanceR41AI116114 · NIAID · IDGENOMICS, INC. · PI APRIKIAN, PAVEL, SOKURENKO, EVGENI VENIAMINOVIC · 2015 to 2015
$214k
NIAID NIH HHS R01 AI106007NIAID NIH HHS R41 AI116114NIAID NIH HHS R42 AI116114
6 · The paper itself

Abstract

We report that fluoroquinolone-resistant Escherichia coli are found in feces of 8.8% of healthy women, with most bacteria belonging to pandemic multidrug-resistant ST131-H30R or ST1193 clonal groups. Moreover, these highly uropathogenic clonal groups demonstrate an especially prolonged gut persistence and high rate of bacteriuria without documented urinary tract infection.

Indexed as

BacteriuriaEscherichia coli InfectionsGastrointestinal MicrobiomeUrinary Tract InfectionsUropathogenic Escherichia coliAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialFemaleFluoroquinolonesHumansPandemicsAnti-Bacterial AgentsFluoroquinolonesbacteriuriaEscherichia colifluoroquinolone resistancegut microfloraurinary tract infections

Identifiers

PMID31271206
PMCPMC7931843
OpenAlexW2955689457

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.