Evidence map›Paper›PMID 31270972›Full record

ReviewKorean journal of radiology2019

Response Assessment with MRI after Chemoradiotherapy in Rectal Cancer: Current Evidences.

Nieun Seo, Honsoul Kim, Min Soo Cho, Joon Seok Lim

Registry-linked trialAbstract readReview
In one paragraph

Review in Korean journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05496491 (Neoadjuvant Chemoradiotherapy and Consolidation Chemotherapy for Rectal Cancer), which is not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05496491 narecruitingnot on this mapstarted 2022, after this paper: background citation

Neoadjuvant Chemoradiotherapy and Consolidation Chemotherapy for Rectal Cancer: A Randomized Controlled Trial

TypeinterventionalSponsorLarissa University HospitalRan2022 to 2029Enrolled84ConditionsRectal NeoplasmsArmsNeoadjuvant Chemoradiotherapy, Adjuvant Chemotherapy, Consolidation Chemotherapy
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  19. MRI for nodal restaging after neoadjuvant therapy in rectal cancer with histopathologic comparison.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nieun Seo *Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0001-8745-6454
Honsoul Kim *Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID 0000-0002-2367-234X
Min Soo ChoDepartment of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-7310-4893
Joon Seok LimDepartment of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. jslim1@yuhs.ac.ORCID 0000-0002-0334-5042

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Baseline magnetic resonance imaging (MRI) has become the primary staging modality for surgical plans and stratification of patient populations for more efficient neoadjuvant treatment. Patients who exhibit a complete response to chemoradiotherapy (CRT) may achieve excellent local tumor control and better quality of life with organ-preserving treatments such as local excision or even watch-and-wait management. Therefore, the evaluation of tumor response is a key factor for determining the appropriate treatment following CRT. Although post-CRT MRI is generally accepted as the first-choice method for evaluating treatment response after CRT, its application in the clinical decision process is not fully validated. In this review, we will discuss various oncologic treatment options from radical surgical technique to organ-preservation strategies for achieving better cancer control and improved quality of life following CRT. In addition, the current status of post-CRT MRI in restaging rectal cancer as well as the main imaging features that should be evaluated for treatment planning will also be described for the tailored treatment.

Indexed as

ChemoradiotherapyFemaleHumansMagnetic Resonance ImagingMaleNeoadjuvant TherapyNeoplasm StagingQuality of LifeRectal NeoplasmsRemission InductionTreatment OutcomeMagnetic resonance imagingNeoadjuvant chemoradiotherapyPathological complete responseRectal cancerTumor response

Identifiers

PMID31270972
PMCPMC6609432

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.