Evidence map›Paper›PMID 31270937›Full record

ArticleJournal of applied clinical medical physics2019

Evaluation of auto-planning in IMRT and VMAT for head and neck cancer.

Zi Ouyang, Zhilei Liu Shen, Eric Murray, Matt Kolar, Danielle LaHurd, Naichang Yu, Nikhil Joshi, Shlomo Koyfman, Karl Bzdusek, Ping Xia

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
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  11. Article
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  14. A Novel Method for Improving VMAT Plan Quality and Deliverability.Asian Pacific journal of cancer prevention : APJCP · 2022
    Article
  15. Review
  16. Artificial Intelligence in Radiation Therapy.IEEE transactions on radiation and plasma medical sciences · 2022
    Article
  17. Article
  18. Evaluation of automatic VMAT plans in locally advanced nasopharyngeal carcinoma.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zi OuyangDepartment of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA.
Zhilei Liu ShenDepartment of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA.
Eric MurrayDepartment of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA.
Matt KolarDepartment of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA.
Danielle LaHurdDepartment of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA.
Naichang YuDepartment of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA.
Nikhil JoshiDepartment of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA.
Shlomo KoyfmanDepartment of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA.
Karl BzdusekPhilips Healthcare Inc, Fitchburg, WI, USA.
Ping XiaDepartment of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863Philips Healthcare Inc.
6 · The paper itself

Abstract

purposeThe purposes of this work are to (a) investigate whether the use of auto-planning and multiple iterations improves quality of head and neck (HN) radiotherapy plans; (b) determine whether delivery methods such as step-and-shoot (SS) and volumetric modulated arc therapy (VMAT) impact plan quality; (c) report on the observations of plan quality predictions of a commercial feasibility tool. MATERIALS AND

methodsTwenty HN cases were retrospectively selected from our clinical database for this study. The first ten plans were used to test setting up planning goals and other optimization parameters in the auto-planning module. Subsequently, the other ten plans were replanned with auto-planning using step-and-shoot (AP-SS) and VMAT (AP-VMAT) delivery methods. Dosimetric endpoints were compared between the clinical plans and the corresponding AP-SS and AP-VMAT plans. Finally, predicted dosimetric endpoints from a commercial program were assessed.

resultsAll AP-SS and AP-VMAT plans met the clinical dose constraints. With auto-planning, the dose coverage of the low dose planning target volume (PTV) was improved while the dose coverage of the high dose PTV was maintained. Compared to the clinical plans, the doses to critical organs, such as the brainstem, parotid, larynx, esophagus, and oral cavity were significantly reduced in the AP-VMAT (P < 0.05); the AP-SS plans had similar homogeneity indices (HI) and conformality indices (CI) and the AP-VMAT plans had comparable HI and improved CI. Good agreement in dosimetric endpoints between predictions and AP-VMAT plans were observed in five of seven critical organs.

conclusionWith improved planning quality and efficiency, auto-planning module is an effective tool to enable planners to generate HN IMRT plans that are meeting institution specific planning protocols. DVH prediction is feasible in improving workflow and plan quality.

Indexed as

Head and Neck NeoplasmsHumansOrgans at RiskRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedRetrospective Studiesauto-planninghead and neckIMRTstep and shootVMAT

Identifiers

PMID31270937
PMCPMC6612692

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.