Evidence map›Paper›PMID 31270714›Full record

ArticleMagma (New York, N.Y.)2019

Evaluation of contrast agent dose and diffusion coefficient measurement on vessel size index estimation.

Behrouz Vejdani Afkham, Sadegh Masjoodi, Mohammad Ali Oghabian, Seyed Roholah Ghodsi, Mohammad Reza Nazem Zadeh, Ebrahim Esmati, Mostafa Farzin, Maziar Gilasi, Hasan Hashemi

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Behrouz Vejdani AfkhamMedical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Sadegh MasjoodiMedical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Ali OghabianMedical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Seyed Roholah GhodsiDevelopment Center of Tehran University of Medical Science, Tehran, Iran.
Mohammad Reza Nazem ZadehResearch Center for Science and Technology in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Ebrahim EsmatiRadiation Oncology, Cancer Institute, Tehran University of Medical Science, Tehran, Iran.
Mostafa FarzinBrain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Maziar GilasiMedical Imaging Center, Imam Khomeini Hospital, Tehran, Iran.
Hasan HashemiAdvanced Diagnostic and Interventional Radiology Research Center (ADIR), Tehran University of Medical Sciences, Tehran, Iran. Hashemi_mic@yahoo.com.

Funding

Tehran University of Medical Sciences and Health Services 96-03-30-36318
6 · The paper itself

Abstract

objectivesThe goal of this study is to examine the effect of contrast agent (CA) dose and diffusion coefficient on the estimation of vessel size index (VSI). MATERIALS AND

methodsThree groups of four participants were enrolled in this study and two different experiments were performed. Different dose of CA, namely 0.1 mmol/kg and 0.05 mmol/kg were assessed in two groups of normal subjects. Diffusion coefficient effect was assessed in the third group with high-grade glioma. Imaging included gradient echo and spin-echo DSC and DTI on a 3-T MR Scanner.

resultsVSI estimation using half of standard dose of CA showed higher values compared to the application of standard, with a ratio of 2 for the WM and 1.5 for the GM. VSI estimates for tumor tissues (22 µm) were considerably higher compared to contra-lateral Normal-Appearing WM (NAWM, 4 µm, P < 0.01) and Normal-Appearing GM (NAGM, 8 µm, P < 0.04). DISCUSSION: Application of standard dose for CA injection and also taking into account the effect of diffusion coefficient can lead to a better correlation of VSI with previous theoretically predicted values and improvement of individual diagnostics in tumor evaluations.

Indexed as

Diffusion Magnetic Resonance ImagingDiffusion Tensor ImagingAdultBlood-Brain BarrierBlood VesselsBrainBrain NeoplasmsContrast MediaGliomaHumansImage Processing, Computer-AssistedMagnetic Resonance SpectroscopyMiddle AgedContrast MediaContrast agentDiffusion tensor imagingDynamic susceptibility contrastVessel size index

Identifiers

PMID31270714

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.