ArticleActa neurochirurgica2019
Management of perineural (Tarlov) cysts: a population-based cohort study and algorithm for the selection of surgical candidates.
Article in Acta neurochirurgica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05059275 (Study on Pathogenesis and Treatment of Sacral Tarlov Cysts), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Study on Pathogenesis and Treatment of Sacral Tarlov Cysts
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Global incidence of spinal perineural Tarlov's cysts and their morphological characteristics: a meta-analysis of 13,266 subjects.Surgical and radiologic anatomy : SRA · 2021Pooled it
- Presacral meningocele presenting after rupture into the retroperitoneal space with acute debilitating intracranial hypotension: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Tarlov Cyst with Pelvic Extension Mimicking an Adnexal Mass: A Case Report.Clinical case reports · 2026Article
- Tarlov cysts and sexual dysfunction: A multidisciplinary approach to evaluation and surgical treatment.North American Spine Society journal · 2026Article
- Article
- [Significance of precise classification of sacral meningeal cysts by multiple dimensions radiographic reconstruction MRI in guiding operative strategy and rehabilitation].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025Article
- Operative Treatment of Tarlov Cysts - Outcomes and Predictors of Improvement after Surgery: A Series of 97 Consecutive Patients and a Systematic Review of Literature.Global spine journal · 2025Article
- Tarlov cyst: A rare cause of radiculopathy.Surgical neurology international · 2025Article
- Integrative Physiotherapy Management of Cervical Radiculopathy and Concurrent Tarlov Cysts.Cureus · 2024Article
- A Case of Symptomatic Multiple Tarlov Cysts Treated with Microsurgical Wrapping Technique -Efficacy and Limitation of Surgical Procedure.NMC case report journal · 2024Article
- Management of Tarlov cysts: an uncommon but potentially serious spinal column disease-review of the literature and experience with over 1000 referrals.Neuroradiology · 2024Review
- A Hidden Condition: Multiple Tarlov Cysts Unveiled in a Young Woman Seeking Primary Care for Debilitating Low Back Pain.The American journal of case reports · 2023Article
- A bibliometric and visualization study of global research trends in sacral Tarlov cyst from 2000 to 2022.Frontiers in surgery · 2023Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePerineural cysts, also known as Tarlov cysts, are cerebrospinal fluid-filled growths that develop at the intersection of a dorsal root ganglion and posterior nerve root. They are typically an asymptomatic and incidental finding during routine spine imaging. For symptomatic perineural cysts, there is little evidence on which treatment is most effective or when it is indicated. The aim of this study was to review our experience from a population-based cohort of patients with symptomatic perineural cysts and to propose an algorithm that could be used in the selection of surgical candidates.
methodsA retrospective review was conducted of all adult (≥ 15 years) patients with symptomatic perineural cysts who were referred to Karolinska University Hospital between 2002 and 2018.
resultsThirty-nine patients were included. The most common symptom was sciatica (n = 22). Cyst aspiration was performed in 28 patients, 24 of whom showed clinical improvement and were offered surgery. Microsurgical cyst fenestration was performed in 17 patients, 16 of whom showed clinical improvement at long-term follow-up. There were no surgical complications. Ten of the patients who were offered surgery chose to be treated conservatively instead, four of whom showed progression of symptoms at long-term follow-up.
conclusionsMicrosurgical cyst fenestration seems to be a safe and effective option for symptomatic relief in patients with perineural cysts. Based on the results from our series and those of others, we propose an algorithm for the selection of surgical candidates.
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