ArticleIntensive care medicine2019
Epidemiology of childhood death in Australian and New Zealand intensive care units.
Article in Intensive care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Scoring Systems for Organ Dysfunction and Multiple Organ Dysfunction: The PODIUM Consensus Conference.Pediatrics · 2022Pooled it
- Bereavement care practices: A national survey of Australian paediatric intensive care units.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026Article
- A Retrospective Epidemiological Study of Mortality in a Pediatric Intensive Care Unit: Trends, Causes, and Risk Factors (2014-2023).Children (Basel, Switzerland) · 2026Article
- Burnout among medical doctors working in paediatric intensive care units in Bulgaria.Frontiers in pediatrics · 2026Article
- Improving Intensive End-of-Life Care for Infants and Children: A Scoping Review of Intervention Elements.Children (Basel, Switzerland) · 2025Review
- Prediction cardiovascular deterioration in a paediatric intensive care unit (PicEWS): a machine learning modelling study of routinely collected health-care data.EClinicalMedicine · 2025Article
- Complex Decision-Making in Paediatric Intensive Care: A Discussion Paper and Suggested Model.Journal of bioethical inquiry · 2025Article
- Forging an easier path through graduation: Improving the patient transition from paediatric to adult critical care.World journal of critical care medicine · 2025Review
- The Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG): 20 Years of Collaborative Research.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025Article
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- Article
- Machine learning to predict poor school performance in paediatric survivors of intensive care: a population-based cohort study.Intensive care medicine · 2023Article
- Evaluation of Changes in Quadriceps Femoris Muscle in Critically III Children Using Ultrasonography.Indian journal of pediatrics · 2023Article
- Characteristics and timing of mortality in children dying in pediatric intensive care: a 5-year experience.Acute and critical care · 2022Article
- Paediatric death after withdrawal of life-sustaining therapies: a scoping review protocol.BMJ open · 2022Article
- Development of a factorial survey for use in an international study examining clinicians' likelihood to support the decision to initiate invasive long-term ventilation for a child (the TechChild study).BMC medical research methodology · 2022Article
- Article
- The brain in pediatric critical care: unique aspects of assessment, monitoring, investigations, and follow-up.Intensive care medicine · 2022Review
- A "Good Death" for Children with Cardiac Disease.Pediatric cardiology · 2022Article
- Is this as good as it gets? Implications of an asymptotic mortality decline and approaching the nadir in pediatric intensive care.European journal of pediatrics · 2022Review
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeData on childhood intensive care unit (ICU) deaths are needed to identify changing patterns of intensive care resource utilization. We sought to determine the epidemiology and mode of pediatric ICU deaths in Australia and New Zealand (ANZ).
methodsThis was a retrospective, descriptive study of multicenter data from pediatric and mixed ICUs reported to the ANZ Pediatric Intensive Care Registry and binational Government census. All patients < 16 years admitted to an ICU between 1 January 2006 and 31 December 2016 were included. Primary outcome was ICU mortality. Subject characteristics and trends over time were evaluated.
resultsOf 103,367 ICU admissions, there were 2672 (2.6%) deaths, with 87.6% of deaths occurring in specialized pediatric ICUs. The proportion of ANZ childhood deaths occurring in ICU was 12%, increasing by 43% over the study period. Unadjusted (0.1% per year, 95% CI 0.096-0.104; p < 0.001) and risk-adjusted (0.1%/year, 95% CI 0.07-0.13; p < 0.001) ICU mortality rates fell. Across all admission sources and diagnostic groups, mortality declined except following pre-ICU cardiopulmonary arrest where increased mortality was observed. Half of the deaths followed withdrawal of life-sustaining therapy (51%), remaining constant throughout the study. Deaths despite maximal resuscitation declined (0.92%/year, 95% CI 0.89-0.95%; p < 0.001) and brain death diagnoses increased (0.72%/year, 95% CI 0.69-0.75%; p = 0.001).
conclusionsUnadjusted and risk-adjusted mortality for children admitted to ANZ ICUs is declining. Half of pediatric ICU deaths follow withdrawal of life-sustaining therapy. Epidemiology and mode of pediatric ICU death are changing. Further investigation at an international level will inform benchmarking, resource allocation and training requirements for pediatric critical care.
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