ArticleThe Journal of experimental medicine2019
Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines.
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Article in The Journal of experimental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers.
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113citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
What it found
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Who cites it
113 citing papers in PubMed, 172 citations in OpenAlex.
- Multisystem inflammation and susceptibility to viral infections in human ZNFX1 deficiency.The Journal of allergy and clinical immunology · 2021Trial
- Prevalence of neutralizing autoantibodies against type I interferon in dengue patients.Journal of human immunity · 2026Article
- Highly neutralizing anti-IFN-ω autoantibodies underlie severe pediatric adenovirus infection.Journal of human immunity · 2026Article
- Guideline for the Diagnosis and Management of Heritable IFNAR1 Deficiency in Oceania.Journal of paediatrics and child health · 2026Review
- Interferon-α and -β subtypes have temporally distinct roles in containing viral spread and protecting vital organs.Research square · 2026Article
- Autoantibodies neutralizing type I IFNs in patients with fulminant herpes simplex virus hepatitis.The Journal of experimental medicine · 2026Article
- Monogenic disorders of immunity: Common variants are not so rare.Cell genomics · 2026Review
- Auto-Abs against type I IFNs: Strong, common, and global determinants of severe arboviral diseases.Journal of human immunity · 2026Review
- GDIv2: improving variant selection from human exomes.Bioinformatics advances · 2026Article
- De novo protein-coding gene variants in developmental stuttering.Molecular psychiatry · 2026Article
- Immunological and transcriptomic profile of chimeric live-attenuated Zika vaccine linked to protection in non-human primates.Nature communications · 2025Article
- The seven enigmas of SARS-CoV-2: from the past to the future.Journal of human immunity · 2025Article
- Review
- Two mutations in NS2B are responsible for attenuation of the yellow fever virus (YFV) vaccine strain 17D.PLoS pathogens · 2025Article
- Interferon-induced activation of dendritic cells and monocytes by yellow fever vaccination correlates with early antibody responses.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection.The Journal of experimental medicine · 2025Article
- Decoding Immunobiology Through Genetic Errors of Immunity.Annual review of immunology · 2025Review
- Mitochondrial hyperactivity and reactive oxygen species drive innate immunity to the yellow fever virus-17D live-attenuated vaccine.PLoS pathogens · 2025Article
- A common form of dominant human IFNAR1 deficiency impairs IFN-α and -ω but not IFN-β-dependent immunity.The Journal of experimental medicine · 2025Article
- Human genetics of responses to vaccines.Clinical and experimental immunology · 2025Review
53 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
50 authors at 18 institutions in 8 countries.
Nicholas Hernandez *St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY.
Giorgia Bucciol *Laboratory of Inborn Errors of Immunity, Department of Immunology, Microbiology and Transplantation, KU Leuven, Leuven, Belgium.ORCID 0000-0001-5004-0738
Leen Moens *Laboratory of Inborn Errors of Immunity, Department of Immunology, Microbiology and Transplantation, KU Leuven, Leuven, Belgium.
Jérémie Le Pen *Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY.
Mohammad Shahrooei *Specialized Immunology Laboratory of Dr. Shahrooei, Sina Medical Complex, Ahvaz, Iran.ORCID 0000-0002-4974-3441
Ekaterini Goudouris *Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0002-1937-9124
Afshin Shirkani *Allergy and Clinical Immunology Department, Bushehr University of Medical Science, School of Medicine, Bushehr, Iran.ORCID 0000-0002-0514-3620
Majid Changi-Ashtiani *School of Mathematics, Institute for Research in Fundamental Sciences, Tehran, Iran.
Hassan Rokni-Zadeh *Department of Medical Biotechnology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Esra Hazar SayarDepartment of Pediatrics, Division of Pediatric Immunology and Allergy, Necmettin Erbakan University, Meram Medical Faculty, Konya, Turkey.ORCID 0000-0003-0338-1040
Ismail ReisliDepartment of Pediatrics, Division of Pediatric Immunology and Allergy, Necmettin Erbakan University, Meram Medical Faculty, Konya, Turkey.
Alain Lefevre-UtilePediatrics Department, Jean Verdier Hospital, Assistance Publique des Hôpitaux de Paris, Paris 13 University, Bondy, France.ORCID 0000-0002-3262-5334
Dick ZijlmansLaboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY.
Andrea JuradoLaboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY.
Ruben PholienLaboratory of Virology and Chemotherapy, Department of Microbiology and Immunology, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.ORCID 0000-0002-4706-5747
Scott DrutmanSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY.ORCID 0000-0002-4222-5684
Serkan BelkayaSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY.ORCID 0000-0003-4214-382X
Aurelie CobatPediatric Immunology-Hematology Unit, Assistance Publique-Hôpitaux de Paris, Necker Hospital for Sick Children, Paris, France.ORCID 0000-0001-7209-6257
Robbert BoudewijnsLaboratory of Virology and Chemotherapy, Department of Microbiology and Immunology, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.ORCID 0000-0002-5984-7279
Dirk JochmansLaboratory of Virology and Chemotherapy, Department of Microbiology and Immunology, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.ORCID 0000-0002-9265-6028
Johan NeytsLaboratory of Virology and Chemotherapy, Department of Microbiology and Immunology, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.ORCID 0000-0002-0033-7514
Yoann SeeleuthnerParis Descartes University, Imagine Institute, Paris, France.
Lazaro Lorenzo-DiazParis Descartes University, Imagine Institute, Paris, France.
Chibuzo EnemchukwuLaboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY.
Ian TietjenLaboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY.
Hans-Heinrich HoffmannLaboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY.ORCID 0000-0003-0554-0244
Mana MomenilandiSpecialized Immunology Laboratory of Dr. Shahrooei, Sina Medical Complex, Ahvaz, Iran.
Laura PöyhönenSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY.
Marilda M SiqueiraNational Reference Laboratory for Respiratory Viruses, Institute Oswaldo Cruz, Fiocruz, Ministry of Health, Rio de Janeiro, Brazil.
Sheila M Barbosa de LimaLaboratory of Virological Techniques, Bio-Manguinhos, Fiocruz, Ministry of Health, Rio de Janeiro, Brazil.
Denise C de Souza MatosLaboratory of Immunological Techniques, Bio-Manguinhos, Fiocruz, Ministry of Health, Rio de Janeiro, Brazil.
Akira HommaBio-Manguinhos, Fiocruz, Ministry of Health, Rio de Janeiro, Brazil.
Maria de Lourdes S MaiaBio-Manguinhos, Fiocruz, Ministry of Health, Rio de Janeiro, Brazil.
Tamiris Azamor da Costa BarrosLaboratory of Immunological Techniques, Bio-Manguinhos, Fiocruz, Ministry of Health, Rio de Janeiro, Brazil.
Patricia Mouta Nunes de OliveiraBio-Manguinhos, Fiocruz, Ministry of Health, Rio de Janeiro, Brazil.
Emersom Ciclini MesquitaBio-Manguinhos, Fiocruz, Ministry of Health, Rio de Janeiro, Brazil.
Rik GijsbersLaboratory for Viral Vector Technology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Shen-Ying ZhangSt. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY.ORCID 0000-0002-9449-3672
Stephen J Seligman *St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY.ORCID 0000-0001-7036-3323
Laurent Abel *St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY.ORCID 0000-0001-7016-6493
Paul Hertzog *Hudson Institute of Medical Research, Clayton, Victoria, Australia.
Nico Marr *Division of Translational Medicine, Sidra Medicine, Doha, Qatar.ORCID 0000-0002-1927-7072
Reinaldo de Menezes Martins *Bio-Manguinhos, Fiocruz, Ministry of Health, Rio de Janeiro, Brazil.
Isabelle Meyts *Laboratory of Inborn Errors of Immunity, Department of Immunology, Microbiology and Transplantation, KU Leuven, Leuven, Belgium.
Qian Zhang *St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY.
Margaret R MacDonald *Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY.ORCID 0000-0001-5177-2068
Charles M Rice *Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY.
Jean-Laurent Casanova *St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY casanova@rockefeller.edu.ORCID 0000-0002-7782-4169
Emmanuelle Jouanguy *St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY.ORCID 0000-0002-7358-9157
Xavier Bossuyt *Department of Microbiology, Immunology and Transplantation, Clinical and Diagnostic Immunology, KU Leuven, Leuven, Belgium.
Rockefeller University · USMinistério da Saúde · BRInserm · FRKU Leuven · BERega Institute for Medical Research · BENecmettin Erbakan University · TRSina Hospital · IRAssistance Publique – Hôpitaux de Paris · FRBushehr University of Medical Sciences · IRChild Health and Development Institute · USHamad bin Khalifa University · QAHoward Hughes Medical Institute · USHudson Institute of Medical Research · AUInstitute for Research in Fundamental Sciences · IRNew York Medical College · USUniversidade Federal do Rio de Janeiro · BRUniversité Sorbonne Paris Nord · FRZanjan University of Medical Sciences · IR
Funding
Using a tonsil organoid system to probe conditions for the induction of protective antibody and T cell responses to influenza.U19AI057229 · NIAID · STANFORD UNIVERSITY · PI Mark Morris Davis · 2003 to 2026
$88.5MWeill Cornell/Rockefeller/Sloan-Kettering MST ProgramT32GM007739 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI HSU, KATHARINE C · 1985 to 2023
$51.1MDeveloping, Demonstrating, and Disseminating Innovative Programs to Achieve Translational SuccessUL1TR001866 · NCATS · ROCKEFELLER UNIVERSITY · PI COLLER, BARRY, KRUEGER, JAMES G · 2016 to 2025
$40.6MUnderstanding B cell memory in response to diverse virus infectionsU19AI111825 · NIAID · ROCKEFELLER UNIVERSITY · PI BOURNAZOS, STYLIANOS · 2014 to 2023
$26.0MUnraveling yellow fever 17D vaccine attenuation: The role of type I interferon and innate immunityR01AI124690 · NIAID · ROCKEFELLER UNIVERSITY · PI Charles M Rice · 2016 to 2026
$8.3MGenetics and Cell BiologyT32GM066699 · NIGMS · ROCKEFELLER UNIVERSITY · PI STRICKLAND, SIDNEY · 2004 to 2021
$7.6MInherited IRF9 deficiency: a novel genetic etiology of severe influenzaR21AI137371 · NIAID · ROCKEFELLER UNIVERSITY · PI CASANOVA, JEAN-LAURENT · 2018 to 2019
$466kNCATS NIH HHS UL1 TR001866NIAID NIH HHS R01 AI124690NIAID NIH HHS R21 AI137371NIAID NIH HHS U19 AI057229NIAID NIH HHS U19 AI111825NIGMS NIH HHS T32 GM007739NIGMS NIH HHS T32 GM066699
Abstract
Vaccination against measles, mumps, and rubella (MMR) and yellow fever (YF) with live attenuated viruses can rarely cause life-threatening disease. Severe illness by MMR vaccines can be caused by inborn errors of type I and/or III interferon (IFN) immunity (mutations in
Indexed as
AdolescentAllelesChildFemaleHumansImmunityInfantInheritance PatternsInterferon Type IMaleMeasles VaccineMutant ProteinsMutationPedigreeReceptor, Interferon alpha-betaSignal TransductionIFNAR1 protein, humanInterferon Type IMeasles VaccineMutant ProteinsReceptor, Interferon alpha-betaYellow Fever Vaccine
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.