Evidence map›Paper›PMID 31270174›Full record

ArticlemSphere2019

Identification of Mutations in the

Srijan Ranjitkar, Folkert Reck, Xiaobo Ke, Qingming Zhu, Glenn McEnroe, Sara L Lopez, Charles R Dean

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. UropathogenicAntibiotics (Basel, Switzerland) · 2026
    Review
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  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. UropathogenicMicroorganisms · 2023
    Review
  15. Review
  16. Article
  17. Article
  18. Genomic characterization of carbapenem-non-susceptibleEmerging microbes & infections · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Srijan RanjitkarInfectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, California, USA.
Folkert ReckInfectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, California, USA.
Xiaobo KeChemical Biology and Therapeutics, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, USA.
Qingming ZhuInfectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, California, USA.
Glenn McEnroeInfectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, California, USA.
Sara L LopezInfectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, California, USA.
Charles R DeanInfectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, California, USA deancr10@yahoo.com.ORCID 0000-0001-9858-9818
Novartis (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Penicillin-binding proteins (PBPs) are essential for bacterial cell wall biosynthesis, and several are clinically validated antibacterial targets of β-lactam antibiotics. We identified mutations in the

Indexed as

Anti-Bacterial AgentsAzabicyclo Compoundsbeta-Lactamasesbeta-Lactam Resistancebeta-LactamsCarbapenemsEscherichia coliEscherichia coli ProteinsMicrobial Sensitivity TestsMutationPenicillin-Binding ProteinsPeptidoglycan GlycosyltransferaseAnti-Bacterial AgentsAzabicyclo Compoundsbeta-lactamase NDM-1beta-Lactamasesbeta-LactamsCarbapenemsEscherichia coli ProteinsFtsI protein, E coliMrdA protein, E coliPenicillin-Binding ProteinsPeptidoglycan GlycosyltransferasecarbapenemsdiazabicyclooctaneNDM-1penicillin-binding proteins

Identifiers

PMID31270174
PMCPMC6609223
OpenAlexW2954877652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.