Evidence map›Paper›PMID 31270172›Full record

ArticlemSphere2019

The Nuclear Export Receptors TbMex67 and TbMtr2 Are Required for Ribosome Biogenesis in Trypanosoma brucei.

Constance Rink, Martin Ciganda, Noreen Williams

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Constance Rink *Department of Microbiology and Immunology, University at Buffalo, Buffalo, New York, USA.
Martin Ciganda *Department of Microbiology and Immunology, University at Buffalo, Buffalo, New York, USA.
Noreen WilliamsDepartment of Microbiology and Immunology, University at Buffalo, Buffalo, New York, USA nw1@buffalo.edu.
University at Buffalo, State University of New York · US

Funding

Ribosomal biogenesis in trypanosomesR01GM110227 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WILLIAMS, NOREEN · 2014 to 2017
$1.2M
Targeting the trypanosomal preribosomal complexR01GM113890 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WILLIAMS, NOREEN · 2015 to 2018
$1.1M
NIGMS NIH HHS R01 GM110227NIGMS NIH HHS R01 GM113890
6 · The paper itself

Abstract

Ribosomal maturation is a complex and highly conserved biological process involving migration of a continuously changing RNP across multiple cellular compartments. A critical point in this process is the translocation of individual ribosomal subunits (60S and 40S) from the nucleus to the cytoplasm, and a number of export factors participate in this process. In this study, we characterize the functional role of the auxiliary export receptors TbMex67 and TbMtr2 in ribosome biogenesis in the parasite

Indexed as

Active Transport, Cell NucleusOrganelle BiogenesisProtozoan ProteinsRibosomal ProteinsRibosomesRNA, MessengerTrypanosoma brucei bruceiProtozoan ProteinsRibosomal ProteinsRNA, Messengernuclear exportprotein-protein interactionsprotein-RNA interactionsribosome biogenesis

Identifiers

PMID31270172
PMCPMC6609230
OpenAlexW2954017720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.