Evidence map›Paper›PMID 31270133›Full record

ArticleGenetics2019

Plasma Membrane Integrity During Cell-Cell Fusion and in Response to Pore-Forming Drugs Is Promoted by the Penta-EF-Hand Protein PEF1 in

Marcel René Schumann, Ulrike Brandt, Christian Adis, Lisa Hartung, André Fleißner

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. CaJournal of fungi (Basel, Switzerland) · 2022
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Marcel René SchumannInstitut für Genetik, Technische Universität Braunschweig, 38106, Germany.
Ulrike BrandtInstitut für Genetik, Technische Universität Braunschweig, 38106, Germany.
Christian AdisInstitut für Genetik, Technische Universität Braunschweig, 38106, Germany.
Lisa HartungInstitut für Genetik, Technische Universität Braunschweig, 38106, Germany.
André FleißnerInstitut für Genetik, Technische Universität Braunschweig, 38106, Germany a.fleissner@tu-bs.de.
Technische Universität Braunschweig · DE

Funding

Tools for Functional Analysis and Cell BiologyP01GM068087 · NIGMS · DARTMOUTH COLLEGE · PI DUNLAP, JAY C. · 2004 to 2013
$19.3M
NIGMS NIH HHS P01 GM068087
6 · The paper itself

Abstract

Plasma membrane damage commonly occurs during cellular growth and development. To counteract these potentially lethal injuries, membrane repair mechanisms have evolved, which promote the integrity of the lipid bilayer. Although the membrane of fungi is the target of important clinical drugs and agricultural fungicides, the molecular mechanisms which mediate membrane repair in these organisms remain elusive. Here we identify the penta-EF-hand protein PEF1 of the genetic model fungus

Indexed as

Membrane FusionAntifungal AgentsCalcium-Binding ProteinsCell MembraneEF Hand MotifsFungal ProteinsIonophoresNeurospora crassaTomatineAntifungal AgentsCalcium-Binding ProteinsFungal ProteinsIonophoresTomatineantifungal drugcell fusionmembrane repairNeurospora crassapenta-EF-hand protein

Identifiers

PMID31270133
PMCPMC6727798
OpenAlexW2953986355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.