Evidence map›Paper›PMID 31270112›Full record

ArticleBMJ open2019

Blood lead level risk factors and reference value derivation in a cross-sectional study of potentially lead-exposed workers in Iran.

Sareh Nakhaee, Alireza Amirabadizadeh, Samaneh Nakhaee, Mahmood Zardast, Jonathan Schimmel, Jalil Ahmadian-Moghadam, Ayob Akbari, Homeira Mohammadian Darmian, Maryam Mohammadi, Omid Mehrpour

Abstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sareh NakhaeeMedical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran.
Alireza AmirabadizadehMedical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran.
Samaneh NakhaeeMedical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran.
Mahmood ZardastMedical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran.
Jonathan SchimmelDenver Health, Rocky Mountain Poison and Drug Center, Denver, Colorado, USA.
Jalil Ahmadian-MoghadamDepartment of Emergency Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
Ayob AkbariMedical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran.
Homeira Mohammadian DarmianStudent Research Committee, Birjand University of Medical Sciences, Birjand, Iran.
Maryam MohammadiStudent Research Committee, Birjand University of Medical Sciences, Birjand, Iran.
Omid MehrpourMedical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis exploratory investigation aimed to measure blood lead levels and associated risk factors in exposed workers in Iran, and to derive appropriate reference values for blood lead in this population as a means of epidemiological comparison.

designCross-sectional.

settingManufacturing plants with potential lead exposure in Southern Khorasan Province, Iran.

participantsThe study included 630 workers, selected through stratified random sampling. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary measures in this exploratory investigation were venous blood lead concentration (BLC) and associated risk factors of age, gender, work experience, cigarette smoking and history of opium use. The secondary measures were symptoms associated with lead toxicity. Data analyses were conducted using Student's t-test, Mann-Whitney U test, one-way analysis of variance, Kruskal-Wallis test, Spearman correlation coefficient and regression analysis.

resultsMean and median BLCs were 6.5±8.1 μg/dL and 3.9 μg/dL (IQR: 2.9-5.8), respectively. Of the subjects, 85 (13.5%) had BLC ≥10 μg/dL. The derived reference BLC value in this study was 30 μg/dL for men and 14 μg/dL for women. Increasing work experience and age were associated with BLC >10 μg/dL. Radiator manufacturers were up to 12.9 times (95% CI 4.6 to 35, p<0.005) more likely than painters to have BLC >10 μg/dL. Most subjects reported multiple symptoms.

conclusionsThe mean BLC was above the maximum recommended concentration. There was a significant relationship between higher BLC and age or working in a printing factory or radiator manufacturing. These findings can direct efforts towards reducing occupational lead exposure.

Indexed as

AdultCross-Sectional StudiesFemaleHumansIranLeadMaleManufacturing and Industrial FacilitiesMiddle AgedOccupational ExposureReference ValuesRisk FactorsLeadblood leadIranoccupational exposurereference valueworker

Identifiers

PMID31270112
PMCPMC6609121

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.