Evidence map›Paper›PMID 31269827›Full record

Trial reportAnnals of medicine

The elevated CXCL5 levels in circulation are associated with lung function decline in COPD patients and cigarette smoking-induced mouse model of COPD.

Jun Chen, Luqi Dai, Tao Wang, Junyun He, Yashu Wang, Fuqiang Wen

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Annals of medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. γδCellular & molecular immunology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
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  12. Evaluating Novel Protein Phosphatase 2A Activators as Therapeutics for Emphysema.American journal of respiratory cell and molecular biology · 2023
    Article
  13. Animal models and mechanisms of tobacco smoke-induced chronic obstructive pulmonary disease (COPD).Journal of toxicology and environmental health. Part B, Critical reviews · 2023
    Review
  14. Circadian disruption in lung fibroblasts enhances NF-κB activity to exacerbate neutrophil recruitment.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  15. Article
  16. Article
  17. Epithelial Ablation of Miro1/Rhot1 GTPase Augments Lung Inflammation by Cigarette Smoke.Pathophysiology : the official journal of the International Society for Pathophysiology · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jun ChenDivision of Pulmonary Diseases, State Key Laboratory of Biotherapy, West China Hospital, West China School of Medicine, Sichuan University , Chengdu , China.
Luqi DaiDivision of Pulmonary Diseases, State Key Laboratory of Biotherapy, West China Hospital, West China School of Medicine, Sichuan University , Chengdu , China.
Tao WangDivision of Pulmonary Diseases, State Key Laboratory of Biotherapy, West China Hospital, West China School of Medicine, Sichuan University , Chengdu , China.
Junyun HeDepartment of Respiratory Medicine, Hospital of Chengdu office of People's Government of Tibetan Autonomous Region of China , Chengdu , China.
Yashu WangDepartment of Clinical Laboratory, Xinjiang Provincial Corps Hospital Chinese People's Armed Police Forces , Urumqi , China.
Fuqiang WenDivision of Pulmonary Diseases, State Key Laboratory of Biotherapy, West China Hospital, West China School of Medicine, Sichuan University , Chengdu , China.
Sichuan University · CNChinese People's Armed Police ForceState Key Laboratory of BiotherapyTibet Autonomous Region People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAnimalsBiomarkersBronchoalveolar Lavage FluidCase-Control StudiesChemokine CXCL5ChinaCigarette SmokingDisease Models, AnimalFemaleGranulocyte Colony-Stimulating FactorHumansInflammationMaleMiceMice, Inbred C57BLBiomarkersChemokine CXCL5CXCL5 protein, humanGranulocyte Colony-Stimulating FactorChronic obstructive pulmonary diseasecigarette smokeC-X-C motif chemokine 5granulocyte-colony stimulating factorlung function declinemouse model of COPDnose-only exposurereceiver operating characteristic

Identifiers

PMID31269827
PMCPMC7877878
OpenAlexW2954194044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.