ArticleJournal of Korean medical science2019
Trends in Lower Limb Amputation in Patients with Diabetic Foot Based on Vascular Intervention of Peripheral Arterial Disease in Korea: a Population-based Nationwide Study.
Article in Journal of Korean medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 27 citations in OpenAlex.
- Predicting Major Amputation Rates in Diabetic Hindfoot Ulcers With Critical Infection and Ischemia: A Risk-Factor-Based Model.Journal of Korean medical science · 2026Article
- Travel Time to Healthcare and Type 2 Diabetes Mellitus Management in Korea: A Nationwide Retrospective Study.Journal of Korean medical science · 2026Article
- Correlation Between Small Dense Low-Density Lipoprotein and Tissue Perfusion in Diabetic Foot.Journal of Korean medical science · 2026Article
- Creating a Practical Tool for Predicting Major Amputation Rate in Patients With Diabetic Hindfoot Ulcers: Focus on Ischemia and Infection.Journal of Korean medical science · 2025Article
- Effects of L-Ornithine-L-Aspartate on Angiogenesis and Perfusion in Subacute Hind Limb Ischemia: Preliminary Study.Biomedicines · 2024Article
- The Risk of the Aggravation of Diabetic Foot According to Air Quality Factors in the Republic of Korea: A Nationwide Population-Based Study.International journal of environmental research and public health · 2024Article
- Healing refractory livedoid vasculopathy-related skin ulcers by ozone therapy: a case-based review.Rheumatology international · 2024Review
- The future of diabetic wound healing: unveiling the potential of mesenchymal stem cell and exosomes therapy.American journal of stem cells · 2024Review
- Management of diabetic foot ulcers: a narrative review.Journal of Yeungnam medical science · 2023Article
- Protective Effects of Statins on Limb and Cardiovascular Outcomes in Patients with Peripheral Artery Disease and End-Stage Renal Disease.Acta Cardiologica Sinica · 2023Article
- Incidence and Prevalence of Peripheral Arterial Disease in South Korea: Retrospective Analysis of National Claims Data.JMIR public health and surveillance · 2022Article
- Pay-for-performance and continuity of care synergistically reduced amputation of lower extremity in patients with diabetes: a population-based cohort study.BMC health services research · 2022Article
- Trend and Seasonality of Diabetic Foot Amputation in South Korea: A Population-Based Nationwide Study.International journal of environmental research and public health · 2022Article
- Multiple metabolic comorbidities and their consequences among patients with peripheral arterial disease.PloS one · 2022Article
- Interpreting global trends in type 2 diabetes complications and mortality.Diabetologia · 2022Review
- Endovascular Treatment for Critical Limb Ischemia in Type II Diabetes Mellitus Involving Femoropopliteal and Infrapopliteal Segments: Revascularization Strategy.Vascular health and risk management · 2021Article
- Trends in Cardiovascular Complications and Mortality among Patients with Diabetes in South Korea.Diabetes & metabolism journal · 2021Article
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundPeripheral arterial disease (PAD) is known as the greatest risk factor affecting the amputation of diabetic foot. Thus, it is crucial to understand the epidemiology of PAD associated with diabetic foot and the relationship between PTA and amputation in predicting prognosis. However, no such multi-year data are available in Korea. Thus, the purpose of this study was to investigate trends of amputation involving diabetic foot based on vascular interventions for PAD in Korea.
methodsThis study was conducted using six-year data obtained from Health Insurance Review and Assessment Service from January 1, 2011 to December 31, 2016. Our study included data pertaining to diabetic foot, PAD, and vascular intervention codes (percutaneous transluminal angioplasty [PTA, M6597], percutaneous intravascular installation of stent-graft [PIISG, M6605], and percutaneous intravascular atherectomy [PIA, M6620]). We analyzed the number of vascular interventions and minor and major amputations each year. The relationship between annual amputation and vascular intervention was analyzed using χ² test.
resultsThe overall number of vascular interventions increased from 253 (PTA, 111; PIISG, 140; and PIA, 2) in 2011 to 1,230 (PTA, 745; PIISG, 470; and PIA, 15) in 2016. During the same period, the number of minor amputations increased from 2,534 to 3,319 while major amputations decreased from 980 to 956. The proportion of minor amputations among patients who underwent vascular intervention was significantly increased from 19.34% in 2011 to 21.45% in 2016 while the proportion of major amputations among these patients was significantly reduced from 9.88% to 4.27%. In addition, the association between vascular intervention and amputation increased from 0.56 (spearman correlation coefficient) in 2011 to 0.62 in 2016.
conclusionIn diabetic foot patients, increase in vascular intervention resulted in a change in amputation pattern, showing statistically significant correlation.
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