Evidence map›Paper›PMID 31269460›Full record

ArticleBiochimica et biophysica acta. Gene regulatory mechanisms2019

KSRP modulates melanoma growth and efficacy of vemurafenib.

Wenwen Liu, Chu-Fang Chou, Shanrun Liu, David Crossman, Nabiha Yusuf, Yunkun Wu, Ching-Yi Chen

Open access · greenAbstract read
In one paragraph

Article in Biochimica et biophysica acta. Gene regulatory mechanisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Wenwen LiuState Key Laboratory of Structured Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China; University of Chinese Academy of Sciences, Beijing 100049, China; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, United States of America.
Chu-Fang ChouDepartment of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, United States of America.
Shanrun LiuDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, United States of America.
David CrossmanDepartment of Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, United States of America.
Nabiha YusufDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, United States of America.
Yunkun WuProvincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, College of Life Science, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou 350119, China. Electronic address: wuyk@fjnu.edu.cn.
Ching-Yi ChenDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, United States of America. Electronic address: cchen@uab.edu.
University of Alabama at Birmingham · USFujian Normal University · CNUniversity of Chinese Academy of Sciences · CN

Funding

Mechanisms elicited by type I interferons in cutaneous photocarcinogenesisR01AR071157 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI YUSUF, NABIHA · 2016 to 2020
$1.8M
NIAMS NIH HHS R01 AR071157
6 · The paper itself

Abstract

The majority of melanomas carry an oncogenic BRAF mutation (BRAF

Indexed as

Drug Resistance, Neoplasm3' Untranslated RegionsAnimalsCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticGene SilencingHumansMelanomaMiceRNA-Binding ProteinsRNA, MessengerRNA StabilityTrans-ActivatorsTumor Suppressor ProteinsUp-Regulation3' Untranslated RegionsKHSRP protein, humanKLLN protein, humanRNA-Binding ProteinsRNA, MessengerTrans-ActivatorsTumor Suppressor ProteinsVemurafenibKSRPMelanomamRNA decayRNA-binding proteinVemurafenib

Identifiers

PMID31269460
PMCPMC7446395
OpenAlexW2954086559

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.