ArticleCell reports2019
The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis.
Open access · goldAbstract read
In one paragraph
Article in Cell reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 70 citations in OpenAlex.
- IL-1-Activated Inflammatory Cardiac Fibroblasts Exacerbate Acute Coxsackievirus B3 Myocarditis.JACC. Basic to translational science · 2026Article
- Myocardial Immune Niches in Homeostasis and Inflammation.Immunological reviews · 2026Review
- Article
- Impact of Early Diagnosis and Immunosuppressive Therapy on Giant Cell Myocarditis Outcomes: A Review.Life (Basel, Switzerland) · 2026Review
- Myocardial inflammation in myocarditis: mechanisms and therapeutic targets.Frontiers in cardiovascular medicine · 2026Review
- Efferocytosis: The Silent Guardian of Tissue Homeostasis and Cardiovascular Health.Journal of cardiovascular development and disease · 2025Review
- MK2 deficiency decreases mortality in male mice during the inflammatory phase after myocardial infarction.Physiological reports · 2025Article
- Pan-immune-inflammation value: a new predictor of cardiac scar in hospitalized myocarditis patients.Biomarkers in medicine · 2025Article
- Contributions of Noncardiac Organ-Heart Immune Crosstalk and Somatic Mosaicism to Heart Failure: Current Knowledge and Perspectives.Circulation research · 2025Review
- Review
- Mitigating murine acute and chronic Coxsackievirus B3-induced myocarditis with human right atrial appendage-derived stromal cells.Stem cells translational medicine · 2025Article
- Macrophage-derived SPP1 exacerbate myocardial injury by interacting with fibroblasts in viral myocarditis.Biology direct · 2025Article
- The distinct functions of MIF in inflammatory cardiomyopathy.Frontiers in immunology · 2025Review
- Cardiovascular adverse effects of immunotherapy in cancer: insights and implications.Frontiers in oncology · 2025Review
- Review
- Review
- At the heart of inflammation: Unravelling cardiac resident macrophage biology.Journal of cellular and molecular medicine · 2024Review
- The protective role of GATA6iScience · 2024Article
- The roles of Th cells in myocardial infarction.Cell death discovery · 2024Review
- The mMolecular and cellular biochemistry · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 4 institutions in 2 countries.
Xuezhou HouW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Guobao ChenDepartment of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
William Bracamonte-BaranDepartment of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Hee Sun ChoiDepartment of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Nicola L DinyW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Jungeun SungInstitute of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
David HughesDepartment of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD 21205, USA.
Taejoon WonDepartment of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Megan Kay WoodW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Monica V TalorDepartment of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
David Joel HackamDivision of General Pediatric Surgery, Johns Hopkins University and Bloomberg Children's Center, Johns Hopkins Hospital, Baltimore, MD 21218, USA.
Karin KlingelCardiopathology, Institute for Pathology and Neuropathology, University of Tübingen, 72076 Tübingen, Germany.
Giovanni DavogusttoDepartment of Internal Medicine, Division of Cardiovascular Medicine, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Heinrich TaegtmeyerDepartment of Internal Medicine, Division of Cardiovascular Medicine, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Isabelle CoppensW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Jobert G BarinDepartment of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Daniela ČihákováW. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA. Electronic address: cihakova@jhmi.edu.
Johns Hopkins University · USThe University of Texas Health Science Center at Houston · USBloomberg (United States) · USUniversity of Tübingen · DE
Funding
SWITCHING OF METABOLIC GENES IN UNLOADED HEARTR01HL061483 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TAEGTMEYER, HEINRICH · 1999 to 2021
$6.2MMyeloid Cells are Critical in Inflammatory Heart DiseaseR01HL118183 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CIHAKOVA, DANIELA · 2014 to 2023
$4.4MTLR4 Signaling in the Pathogenesis of Surgical Necrotizing EnterocolitisR01GM078238 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HACKAM, DAVID J · 2006 to 2019
$3.9MRole of Sca-1+Cardiac Fibroblasts in Inflammatory Heart Disease`R01HL136586 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CIHAKOVA, DANIELA · 2018 to 2021
$1.6MMaternal-Fetal AHR Signaling in the Pathogenesis and Treatment of Necrotizing EnterocolitisR01DK117186 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI HACKAM, DAVID J · 2018 to 2021
$1.5MAcquisition of a Carl Zeiss Lightsheet Z.1 Fluorescence MicroscopeS10OD020152 · OD · JOHNS HOPKINS UNIVERSITY · PI MCCAFFERY, J. MICHAEL · 2016 to 2016
$597kNHLBI NIH HHS R01 HL061483NHLBI NIH HHS R01 HL118183NHLBI NIH HHS R01 HL136586NIDDK NIH HHS R01 DK117186NIGMS NIH HHS R01 GM078238NIH HHS S10 OD020152
Abstract
Two types of monocytes, Ly6C
Indexed as
AnimalsAntigens, LyCell DifferentiationCell Proliferationc-Mer Tyrosine KinaseDisease Models, AnimalFibroblastsHumansInflammationInterleukin-17MacrophagesMiceMice, Inbred BALB CMice, KnockoutMicroscopy, Electron, TransmissionMonocytesAntigens, Lyc-Mer Tyrosine KinaseInterleukin-17Ly-6C antigen, mouseMertk protein, mouseheartLy6CmacrophagesMerTKmonocytesmyocarditis
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.