ArticleRevista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
Combined influence of illness duration and medication type on visual sensitivity in schizophrenia.
Article in Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review and Meta-Analysis on Contrast Sensitivity in Schizophrenia.Schizophrenia bulletin · 2025Pooled it
- Perceptual Functioning.Current topics in behavioral neurosciences · 2023Article
- Longer illness duration is associated with greater individual variability in functional brain activity in Schizophrenia, but not bipolar disorder.NeuroImage. Clinical · 2022Article
- Cognitive function mediates the relationship between visual contrast sensitivity and functional outcome in schizophrenia.Journal of psychiatric research · 2021Article
- Association between retinal and cortical visual electrophysiological impairments in schizophrenia.Journal of psychiatry & neuroscience : JPNArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePatients with schizophrenia have visual processing impairments. The main findings from the literature indicate that these deficits may be related to differences in paradigms, medications, and illness duration. This study is part of a large-scale study investigating visual sensitivity in schizophrenia. Here we aimed to investigate the combined effects of illness duration and antipsychotic use on contrast sensitivity function.
methodsData were collected from 50 healthy controls and 50 outpatients with schizophrenia (classified according to illness duration and medication type) aged 20-45 years old. The contrast sensitivity function was measured for spatial frequencies ranging from 0.2 to 20 cycles per degree using linear sine-wave gratings.
resultsPatients with an illness duration > 5 years had more pronounced deficits. Differences in the combined effects of illness duration and antipsychotic use were marked in patients on typical antipsychotics who had been ill > 10 years. No significant differences were found between typical and atypical antipsychotics in patients with an illness duration < 5 years.
conclusionVisual impairment was related to both long illness duration and medication type. These results should be tested in further studies to investigate pharmacological mechanisms.
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