Evidence map›Paper›PMID 31268831›Full record

ArticleMolecular biology of the cell2019

DAPLE and MPDZ bind to each other and cooperate to promote apical cell constriction.

Arthur Marivin, Mikel Garcia-Marcos

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Endoscopic third ventriculostomy for diencephalosynapsis-related hydrocephalus in MPDZ gene syndrome: a case report and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Review
  3. A steady-state pool of calcium-dependent actin is maintained by Homer and controls epithelial mechanosensation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Review
  6. Genes & diseases · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. DAPLE protein inhibits nucleotide exchange on GαThe Journal of biological chemistry · 2020
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Arthur MarivinDepartment of Biochemistry, Boston University School of Medicine, Boston, MA 02118.
Mikel Garcia-MarcosDepartment of Biochemistry, Boston University School of Medicine, Boston, MA 02118.
Boston University · US

Funding

Alternative mechanisms of signaling via trimeric G proteinsR01GM108733 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GARCIA-MARCOS, MIKEL · 2014 to 2018
$1.6M
NIGMS NIH HHS R01 GM108733
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell PolarityAnimalsGenes, DominantHEK293 CellsHumansIntercellular JunctionsIntracellular Signaling Peptides and ProteinsMembrane ProteinsMicrofilament ProteinsNeurulationPDZ DomainsProtein BindingXenopus laevisCCDC88C protein, humanIntracellular Signaling Peptides and ProteinsMembrane ProteinsMicrofilament ProteinsMPDZ protein, human

Identifiers

PMID31268831
PMCPMC6727773
OpenAlexW2956089192

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.