Evidence map›Paper›PMID 31268706›Full record

ArticleJournal of the American Chemical Society2019

A Responsive Magnetic Resonance Imaging Contrast Agent for Detection of Excess Copper(II) in the Liver

Namini N Paranawithana, Andre F Martins, Veronica Clavijo Jordan, Piyu Zhao, Sara Chirayil, Gabriele Meloni, A Dean Sherry

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Design of the elusive proteinaceous oxygen donor copper site suggests a promising future for copper for MRI contrast agents.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Fast Ion-Chelate Dissociation Rate forJournal of the American Chemical Society · 2021
    Article
  7. Review
  8. Article
  9. Uniform FeBeilstein journal of nanotechnology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Namini N ParanawithanaDepartment of Chemistry and Biochemistry , University of Texas at Dallas , Richardson , Texas , United States.
Andre F MartinsDepartment of Chemistry and Biochemistry , University of Texas at Dallas , Richardson , Texas , United States.ORCID 0000-0002-0171-0261
Veronica Clavijo JordanAdvanced Imaging Research Center , University of Texas Southwestern Medical Center , Dallas , Texas , United States.ORCID 0000-0002-1468-164X
Piyu ZhaoDepartment of Chemistry and Biochemistry , University of Texas at Dallas , Richardson , Texas , United States.
Sara ChirayilAdvanced Imaging Research Center , University of Texas Southwestern Medical Center , Dallas , Texas , United States.
Gabriele MeloniDepartment of Chemistry and Biochemistry , University of Texas at Dallas , Richardson , Texas , United States.ORCID 0000-0003-4976-1401
A Dean SherryDepartment of Chemistry and Biochemistry , University of Texas at Dallas , Richardson , Texas , United States.ORCID 0000-0001-7150-8301
The University of Texas at Dallas · USSouthwestern Medical Center · US

Funding

TR&D 3: Imaging Carbohydrate MetabolismP41EB015908 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MALLOY, CRAIG R · 2012 to 2021
$10.9M
Imaging Beta Cell Function in Vivo with Zinc Responsive MRI Contrast AgentsR01DK095416 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI SHERRY, DEAN · 2012 to 2021
$3.3M
NIBIB NIH HHS P41 EB015908NIDDK NIH HHS R01 DK095416
6 · The paper itself

Abstract

The design, synthesis, and properties of a new gadolinium-based copper-responsive magnetic resonance imaging (MRI) contrast agent is presented. The sensor (GdL

Indexed as

Magnetic Resonance ImagingAnimalsContrast MediaCoordination ComplexesCopperGadoliniumLiverMiceMice, Inbred C57BLMolecular StructureSerum Albumin, HumanContrast MediaCoordination ComplexesCopperGadoliniumSerum Albumin, Human

Identifiers

PMID31268706
PMCPMC9991518
OpenAlexW2949231902

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.