Evidence map›Paper›PMID 31268192›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2020

Inhibitors of Bacterial Swarming Behavior.

Sina Rütschlin, Thomas Böttcher

Abstract readReview
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
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  6. Article
  7. Review
  8. Article
  9. Article
  10. Short Synthesis of Structurally DiverseInternational journal of molecular sciences · 2025
    Article
  11. Article
  12. sRNA113 regulatesZoological research · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Anti-Biofilm and Anti-Quorum-Sensing Activity ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sina RütschlinDepartment of Chemistry, Konstanz Research, School Chemical Biology, Zukunftskolleg, University of Konstanz, 78457, Konstanz, Germany.
Thomas BöttcherDepartment of Chemistry, Konstanz Research, School Chemical Biology, Zukunftskolleg, University of Konstanz, 78457, Konstanz, Germany.ORCID http://orcid.org/0000-0003-0235-4825

Funding

7th Framework Program European Union EU Marie Curie Zukunftskolleg Incoming FellowshipGerman Research Foundation Emmy Noether programKoRS-CB PhD fellowship
6 · The paper itself

Abstract

Bacteria can migrate in groups of flagella-driven cells over semisolid surfaces. This coordinated form of motility is called swarming behavior. Swarming is associated with enhanced virulence and antibiotic resistance of various human pathogens and may be considered as favorable adaptation to the diverse challenges that microbes face in rapidly changing environments. Consequently, the differentiation of motile swarmer cells is tightly regulated and involves multi-layered signaling networks. Controlling swarming behavior is of major interest for the development of novel anti-infective strategies. In addition, compounds that block swarming represent important tools for more detailed insights into the molecular mechanisms of the coordination of bacterial population behavior. Over the past decades, there has been major progress in the discovery of small-molecule modulators and mechanisms that allow selective inhibition of swarming behavior. Herein, an overview of the achievements in the field and future directions and challenges will be presented.

Indexed as

Anti-Bacterial AgentsBacteriaBacterial ProteinsFlagellaQuinolonesQuorum SensingSignal TransductionSmall Molecule LibrariesAnti-Bacterial AgentsBacterial ProteinsQuinolonesSmall Molecule Librariesflagellainteractionsmotilitynatural productsquorum sensing

Identifiers

PMID31268192
PMCPMC7027876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.