Evidence map›Paper›PMID 31268131›Full record

Trial reportThe American journal of clinical nutrition2019

Time-restricted feeding plus resistance training in active females: a randomized trial.

Grant M Tinsley, M Lane Moore, Austin J Graybeal, Antonio Paoli, Youngdeok Kim, Joaquin U Gonzales, John R Harry, Trisha A VanDusseldorp, Devin N Kennedy, Megan R Cruz

2 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of clinical nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 126 papers, 27 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed, 27 pooled it
13.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03404271 nacompletednot on this map

Time-Restricted Feeding Plus Resistance Training in Active Females: Effects on Body Composition, Muscular Performance and Physiological Variables

TypeinterventionalSponsorTexas Tech UniversityRan2018 to 2018Enrolled40ConditionsHealthy Active FemalesArmsBeta-hydroxy beta-methylbutyrate, Resistance Training, Protein Supplementation, Time-Restricted Feeding
NCT04320784 nacompletednot on this map

Effects of 4 Weeks of Time Restricted Eating Protocol on Performance, Metabolism and Blood Outcomes in Elite Cyclists

TypeinterventionalSponsorUniversity of PadovaRan2018 to 2018Enrolled16ConditionsFasting and PerformanceArmsTime restricted eating, Control
3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 27 syntheses or guidelines pooled it, 211 citations in OpenAlex.

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  20. Intermittent fasting for the prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2021
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66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Grant M TinsleyDepartment of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX, USA.
M Lane MooreDepartment of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX, USA.
Austin J GraybealDepartment of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX, USA.
Antonio PaoliDepartment of Biomedical Sciences, University of Padova, Padova, Italy.
Youngdeok KimDepartment of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX, USA.
Joaquin U GonzalesDepartment of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX, USA.
John R HarryDepartment of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX, USA.
Trisha A VanDusseldorpDepartment of Exercise Science and Sport Management, Kennesaw State University, Kennesaw, GA, USA.
Devin N KennedyDepartment of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX, USA.
Megan R CruzDepartment of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX, USA.
Texas Tech University · USKennesaw State University · USUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA very limited amount of research has examined intermittent fasting (IF) programs, such as time-restricted feeding (TRF), in active populations.

objectiveOur objective was to examine the effects of TRF, with or without β-hydroxy β-methylbutyrate (HMB) supplementation, during resistance training (RT).

methodsThis study employed a randomized, placebo-controlled, reduced factorial design and was double-blind with respect to supplementation in TRF groups. Resistance-trained females were randomly assigned to a control diet (CD), TRF, or TRF plus 3 g/d HMB (TRFHMB). TRF groups consumed all calories between 1200 h and 2000 h, whereas the CD group ate regularly from breakfast until the end of the day. All groups completed 8 wk of supervised RT and consumed supplemental whey protein. Body composition, muscular performance, dietary intake, physical activity, and physiological variables were assessed. Data were analyzed prior to unblinding using mixed models and both intention-to-treat (ITT) and per protocol (PP) frameworks.

resultsForty participants were included in ITT, and 24 were included in PP. Energy and protein intake (1.6 g/kg/d) did not differ between groups despite different feeding durations (TRF and TRFHMB: ∼7.5 h/d; CD: ∼13 h/d). Comparable fat-free mass (FFM) accretion (+2% to 3% relative to baseline) and skeletal muscle hypertrophy occurred in all groups. Differential effects on fat mass (CD: +2%; TRF: -2% to -4%; TRFHMB: -4% to -7%) were statistically significant in the PP analysis, but not ITT. Muscular performance improved without differences between groups. No changes in physiological variables occurred in any group, and minimal side effects were reported.

conclusionsIF, in the form of TRF, did not attenuate RT adaptations in resistance-trained females. Similar FFM accretion, skeletal muscle hypertrophy, and muscular performance improvements can be achieved with dramatically different feeding programs that contain similar energy and protein content during RT. Supplemental HMB during fasting periods of TRF did not definitively improve outcomes. This study was prospectively registered at clinicaltrials.gov as NCT03404271.

Indexed as

MealsResistance TrainingAdultBody CompositionFemaleHumansTime FactorsYoung Adultbody compositionenergy restrictionfat lossintermittent energy restrictionintermittent fastingmuscle massmuscular strengthproteinresistance exerciseweight training

Identifiers

PMID31268131
PMCPMC6735806
OpenAlexW2953470221

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.