Evidence map›Paper›PMID 31267796›Full record

ArticleJournal of the American Heart Association2019

Thresholds for Ambulatory Blood Pressure Monitoring Based on Maternal and Neonatal Outcomes in Late Pregnancy in a Southern Chinese Population.

Li-Juan Lv, Wen-Jie Ji, Lin-Lin Wu, Jun Miao, Ji-Ying Wen, Qiong Lei, Dong-Mei Duan, Huan Chen, Jane E Hirst, Amanda Henry and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Comment on "Morning blood pressure and adverse pregnancy outcomes in high-risk pregnancies".Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  2. Morning Blood Pressure and Adverse Pregnancy Outcomes in High-Risk Pregnancies.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
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  9. Is an office blood pressure ≥140/90 mmHg an appropriate hypertension threshold for pregnant women?Hypertension research : official journal of the Japanese Society of Hypertension · 2025
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  14. Review
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  16. Nocturnal hypertension and risk of developing early-onset preeclampsia in high-risk pregnancies.Hypertension research : official journal of the Japanese Society of Hypertension · 2021
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Li-Juan Lv1 Medical Genetics Centre Guangdong Women and Children Hospital Guangzhou Guangdong Province China.
Wen-Jie Ji3 Tianjin Key Laboratory of Cardiovascular Remodeling and Target Organ Injury Pingjin Hospital Tianjin China.
Lin-Lin Wu4 Shenzhen Maternity and Child Healthcare Hospital Southern Medical University Shenzhen Guangdong Province China.
Jun Miao3 Tianjin Key Laboratory of Cardiovascular Remodeling and Target Organ Injury Pingjin Hospital Tianjin China.
Ji-Ying Wen2 Department of Obstetrics Guangdong Women and Children Hospital Guangzhou Guangdong Province China.
Qiong Lei2 Department of Obstetrics Guangdong Women and Children Hospital Guangzhou Guangdong Province China.
Dong-Mei Duan2 Department of Obstetrics Guangdong Women and Children Hospital Guangzhou Guangdong Province China.
Huan Chen5 The George Institute for Global Health at Peking University Health Science Center (PUHSC) Beijing China.
Jane E Hirst6 The George Institute for Global Health Nuffield Department of Women's & Reproductive Health University of Oxford United Kingdom.
Amanda Henry8 School of Women's and Children's Health UNSW Medicine UNSW Sydney Sydney Australia.
Xin Zhou3 Tianjin Key Laboratory of Cardiovascular Remodeling and Target Organ Injury Pingjin Hospital Tianjin China.
Jian-Min Niu4 Shenzhen Maternity and Child Healthcare Hospital Southern Medical University Shenzhen Guangdong Province China.
Guangdong Province Women and Children Hospital · CNPingjin Hospital · CNGeorge Institute for Global Health · GBGeorge Institute for Global Health · CNShenzhen Maternity and Child Healthcare Hospital · CNSouthern Medical University · CNSt Vincent's Clinic · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background In contrast to the general population, outcome-derived thresholds for diagnosing ambulatory hypertension in pregnancy are not yet available. We aimed to identify and compare outcome-derived ambulatory blood pressure (BP) monitoring thresholds for adverse perinatal outcomes by using approaches related and not related to clinic BP in a southern Chinese population. Methods and Results Ambulatory BP monitoring was performed in a cohort of 1768 high-risk participants in late pregnancy who were not taking antihypertensive medications. Participants were followed for composite maternal (severe complications) and neonatal (pregnancy loss, advanced neonatal care, and small for gestational age) outcomes. Modeling of clinic BP-unrelated approaches revealed a nonlinear threshold effect of ambulatory diastolic BP on the composite outcome, with increased risk for daytime ≥79 mm Hg and 24-hour measurement ≥76 mm Hg. For other ambulatory BP components showing linear associations with outcome, the following thresholds were identified: 131 mm Hg for daytime systolic, 121 mm Hg for nighttime systolic, 130 mm Hg for 24-hour systolic, and 73 mm Hg for night-time diastolic BP. These thresholds unrelated to clinic BP were lower than the equivalents yielding a similar probability of outcome to clinic BP of 140/90 mm Hg and were comparable with equivalents to clinic BP of 130/80 mm Hg. Conclusions Using an outcome-derived approach unrelated to clinic BP, we identified rounded thresholds to define ambulatory hypertension in at-risk women in late pregnancy in a southern Chinese population as follows: 130/80 mm Hg for daytime, 120/75 mm Hg for nighttime, and 130/75 mm Hg for 24-hour measurement. For wider clinical applicability and to align both nonpregnancy and pregnancy ambulatory BP monitoring with an outcomes-based approach, prospective, multiethnic, international studies from early pregnancy onward will be required.

Indexed as

Blood Pressure Monitoring, AmbulatoryAbruptio PlacentaeAdultBlood PressureChinaCircadian RhythmCohort StudiesFemaleHumansHypertension, Pregnancy-InducedInfant, NewbornInfant, Small for Gestational AgeIntensive Care, NeonatalLiver DiseasesMaleMaternal Deathambulatory blood pressure monitoringhypertensionmaternal outcomeneonatal outcomepregnancy

Identifiers

PMID31267796
PMCPMC6662146
OpenAlexW2954266878

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.