Evidence map›Paper›PMID 31267638›Full record

ReviewAngewandte Chemie (International ed. in English)2019

ATP-Mediated Transient Behavior of Stomatocyte Nanosystems.

Hailong Che, Jianzhi Zhu, Shidong Song, Alexander F Mason, Shoupeng Cao, Imke A B Pijpers, Loai K E A Abdelmohsen, Jan C M van Hest

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Angewandte Chemie (International ed. in English), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 64 citations in OpenAlex.

  1. Fast and Autonomous Mannosylated Nanomotors for Dynamic Cancer Cell Targeting.Angewandte Chemie (International ed. in English) · 2025
    Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Achieving Control in Micro-/Nanomotor Mobility.Angewandte Chemie (International ed. in English) · 2023
    Review
  8. Review
  9. Dissipative Organization of DNA Oligomers for Transient Catalytic Function.Angewandte Chemie (International ed. in English) · 2022
    Article
  10. Article
  11. Article
  12. Chemically Fueled Self-Assembly in Biology and Chemistry.Angewandte Chemie (International ed. in English) · 2021
    Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. ATP-Mediated Transient Behavior of Stomatocyte Nanosystems.Angewandte Chemie (International ed. in English) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hailong CheEindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB, Eindhoven, The Netherlands.
Jianzhi ZhuEindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB, Eindhoven, The Netherlands.
Shidong SongEindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB, Eindhoven, The Netherlands.
Alexander F MasonEindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB, Eindhoven, The Netherlands.
Shoupeng CaoEindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB, Eindhoven, The Netherlands.
Imke A B PijpersEindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB, Eindhoven, The Netherlands.
Loai K E A AbdelmohsenEindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB, Eindhoven, The Netherlands.
Jan C M van HestEindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB, Eindhoven, The Netherlands.ORCID 0000-0001-7973-2404
Eindhoven University of Technology · NL

Funding

Dutch Min-istry of Education, Culture and Science Gravitation program 024.001.035Dutch Science Foundation VICI grantEuropean Research Council ERC Advanced grant Artisym 694120European Union's Horizon 2020 research and innovation programme Marie Sklodowska Curie Innovative Training Networks Nanomed, (No. 676137)
6 · The paper itself

Abstract

In nature, dynamic processes are ubiquitous and often characterized by adaptive, transient behavior. Herein, we present the development of a transient bowl-shaped nanoreactor system, or stomatocyte, the properties of which are mediated by molecular interactions. In a stepwise fashion, we couple motility to a dynamic process, which is maintained by transient events; namely, binding and unbinding of adenosine triphosphate (ATP). The surface of the nanosystem is decorated with polylysine (PLL), and regulation is achieved by addition of ATP. The dynamic interaction between PLL and ATP leads to an increase in the hydrophobicity of the PLL-ATP complex and subsequently to a collapse of the polymer; this causes a narrowing of the opening of the stomatocytes. The presence of the apyrase, which hydrolyzes ATP, leads to a decrease of the ATP concentration, decomplexation of PLL, and reopening of the stomatocyte. The competition between ATP input and consumption gives rise to a transient state that is controlled by the out-of-equilibrium process.

Indexed as

Adenosine TriphosphateAnimalsArtificial CellsCell ShapeErythrocytesHumansHydrophobic and Hydrophilic InteractionsNanostructuresNanotechnologyPolylysineAdenosine TriphosphatePolylysineATPnanomotorsnanoreactorsout-of-equilibrium systemsstomatocytes

Identifiers

PMID31267638
PMCPMC7079195
OpenAlexW2954401979

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.