Evidence map›Paper›PMID 31267578›Full record

ArticleMagnetic resonance in medicine2019

Evidence of the diffusion time dependence of intravoxel incoherent motion in the brain.

Dan Wu, Jiangyang Zhang

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Use of Nuclear Magnetic Resonance (NMR) to Study Cancer Metabolism.Advances in experimental medicine and biology · 2026
    Review
  8. Article
  9. Article
  10. In Vivo and Post-mortem Comparisons of IVIM/Time-dependent Diffusion MR Imaging Parameters in Melanoma and Breast Cancer Xenograft Models.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Joint estimation of compartment-specific TMagnetic resonance in medicine · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dan WuKey Laboratory for Biomedical Engineering of Ministry of Education, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, China.ORCID 0000-0002-9303-5821
Jiangyang ZhangBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York.

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Hersh Chandarana · 2014 to 2026
$19.3M
Imaging Neonatal Hypoxic Ischemic InjuryR01HD074593 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FRANCES J NORTHINGTON, JIANGYANG ZHANG · 2013 to 2026
$6.8M
Quantitative Imaging of Mouse Brain DevelopmentR01NS102904 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ZHANG, JIANGYANG · 2018 to 2022
$3.1M
NIBIB NIH HHS P41 EB017183NICHD NIH HHS R01 HD074593NINDS NIH HHS R01 NS102904
6 · The paper itself

Abstract

purposeTo investigate the diffusion time (T

methodsA 3-compartment IVIM model was proposed to characterize 2 types of microcirculatory flows in addition to tissue water in the brain: flows that cross multiple vascular segments (pseudo-diffusive) and flows that stay in 1 segment (ballistic) within T

resultsBy fitting the model to simulated flow signals, we demonstrated the T

conclusionWe demonstrated that IVIM signals measured in the brain are T

Indexed as

Diffusion Magnetic Resonance ImagingMotionAnimalsBrainComputer SimulationImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedMaleMiceMice, Inbred C57BLMicrocirculationPhantoms, ImagingTime Factorscompartmentsdiffusion timeintravoxel incoherent motionmicrocirculationoscillating gradient

Identifiers

PMID31267578
PMCPMC6717033

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.