ArticleInternational journal of computer assisted radiology and surgery2020
Normative ranges of nasal airflow variables in healthy adults.
Article in International journal of computer assisted radiology and surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04220853 (Changes in Nasal Airflow Parameters After Septoplasty and Turbinoplasty), which is not on this map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Changes in Nasal Airflow Parameters After Septoplasty and Turbinoplasty
Who cites it
27 citing papers in PubMed.
- Study of nasal heating function based on 40 cases of nasal cavity model.Scientific reports · 2026Article
- Evaluation of accuracy, filter performance, and durability among capnography sampling lines: a bench study.Journal of clinical monitoring and computing · 2026Article
- Deposition of Occupational Aerosol Particles in a Three-Dimensional Adult Nasal Cavity Model: An Experimental Study.Bioengineering (Basel, Switzerland) · 2026Article
- Article
- Mechanics-guided parametric modeling of intranasal spray devices and formulations for targeted drug delivery to the nasopharynx.Frontiers in drug delivery · 2025Article
- Effects of Mucosal Decongestion on Nasal Aerodynamics: A Pilot Study.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024Article
- Computational Rhinology: Unraveling Discrepancies between In Silico and In Vivo Nasal Airflow Assessments for Enhanced Clinical Decision Support.Bioengineering (Basel, Switzerland) · 2024Review
- Impact of nasal septal perforation on the airflow and air-conditioning characteristics of the nasal cavity.Scientific reports · 2024Article
- Effects of 3D Airway Geometry on the Airflow of Adults with Cleft Lip and Palate and Obstructive Sleep Apnea: A Functional Imaging Study.Sleep science (Sao Paulo, Brazil) · 2023Article
- CT analysis of the anterior nasal airway based on the direction of nasal airflow in patients with nasal obstruction and trauma controls.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
- Acoustic Aerosol Delivery: Assessing of Various Nasal Delivery Techniques and Medical Devices on Intrasinus Drug Deposition.Pharmaceuticals (Basel, Switzerland) · 2023Article
- In Silico Quantification of Intersubject Variability on Aerosol Deposition in the Oral Airway.Pharmaceutics · 2023Article
- Spatial aerosol deposition correlated to anatomic feature development in 6-year-old upper airway computational models.Computers in biology and medicine · 2022Article
- Comparison of rhinomanometric and computational fluid dynamic assessment of nasal resistance with respect to measurement accuracy.International journal of computer assisted radiology and surgery · 2022Article
- Toward automatic atlas-based surgical planning for septoplasty.International journal of computer assisted radiology and surgery · 2022Article
- A systematic analysis of surgical interventions for the airway in the mature unilateral cleft lip nasal deformity: a single case study.International journal of computer assisted radiology and surgery · 2022Article
- Improvements in airflow characteristics and effect on the NOSE score after septoturbinoplasty: A computational fluid dynamics analysis.PloS one · 2022Article
- Nasally inhaled therapeutics and vaccination for COVID-19: Developments and challenges.MedComm · 2021Review
- Nasal airflow of patient with septal deviation and allergy rhinitis.Visual computing for industry, biomedicine, and art · 2021Article
- Existence of a Neutral-Impact Maxillo-Mandibular Displacement on Upper Airways Morphology.Journal of personalized medicine · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
purposeVirtual surgery planning based on computational fluid dynamics (CFD) simulations of nasal airflow has the potential to improve surgical outcomes for patients with nasal airway obstruction (NAO). Virtual surgery planning requires normative ranges of airflow variables, but few studies to date have quantified inter-individual variability of nasal airflow among healthy subjects. This study reports CFD simulations of nasal airflow in 47 healthy adults.
methodsAnatomically accurate three-dimensional nasal models were reconstructed from cone beam computed tomography scans and used for steady-state inspiratory airflow simulations with a bilateral flowrate of 250 ml/s. Normal subjective sensation of nasal patency was confirmed using the nasal obstruction symptom evaluation and visual analog scale. Healthy ranges for several CFD variables known to correlate with subjective nasal patency were computed, including unilateral airflow, nasal resistance, airspace minimal cross-sectional area (mCSA), heat flux (HF), and surface area stimulated by mucosal cooling (defined as the area where HF > 50 W/m
resultsA wide range of inter-individual variability in nasal airflow was observed among healthy subjects. Unilateral airflow varied from 60 to 191 ml/s, airflow partitioning ranged from 23.8 to 76.2%, and unilateral mCSA varied from 0.24 to 1.21 cm
conclusionsThese normative ranges may serve as targets in future virtual surgery planning for patients with NAO.
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