Evidence map›Paper›PMID 31267279›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020

Longitudinal assessment of the impact of higher body mass index on cancer-related fatigue in patients with breast cancer receiving chemotherapy.

Julia E Inglis, Michelle C Janelsins, Eva Culakova, Karen M Mustian, Po-Ju Lin, Ian R Kleckner, Luke J Peppone

Open access · greenAbstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
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  3. The relationship between the latent profiles of cancer-related fatigue characteristics and exercise adherence in colorectal cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
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  5. Article
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  7. Observational
  8. Metabolic underpinnings of cancer-related fatigue.American journal of physiology. Endocrinology and metabolism · 2024
    Review
  9. Review
  10. Too Much, Too Little, or Just Right? Obesity and Dosing of Targeted Therapies in Breast Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Article
  11. Breast cancer survivors with pain: an examination of the relationships between body mass index, physical activity, and symptom burden.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  12. Article
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  14. Baseline fatigue in early breast cancer survivors: understanding its prevalence in community-based exercise.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Julia E InglisDepartment of Surgery, University of Rochester Medical Center (URMC), 265 Crittenden Blvd, CU 420658, Rochester, NY, 14642, USA. Julia_Inglis@URMC.Rochester.edu.ORCID http://orcid.org/0000-0001-8236-0840
Michelle C JanelsinsDepartment of Surgery, University of Rochester Medical Center (URMC), 265 Crittenden Blvd, CU 420658, Rochester, NY, 14642, USA.
Eva CulakovaDepartment of Surgery, University of Rochester Medical Center (URMC), 265 Crittenden Blvd, CU 420658, Rochester, NY, 14642, USA.
Karen M MustianDepartment of Surgery, University of Rochester Medical Center (URMC), 265 Crittenden Blvd, CU 420658, Rochester, NY, 14642, USA.
Po-Ju LinDepartment of Surgery, University of Rochester Medical Center (URMC), 265 Crittenden Blvd, CU 420658, Rochester, NY, 14642, USA.
Ian R KlecknerDepartment of Surgery, University of Rochester Medical Center (URMC), 265 Crittenden Blvd, CU 420658, Rochester, NY, 14642, USA.
Luke J PepponeDepartment of Surgery, University of Rochester Medical Center (URMC), 265 Crittenden Blvd, CU 420658, Rochester, NY, 14642, USA.
University of Rochester Medical Center · US

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
UNIVERSITY OF ROCHESTER--CCOP RESEARCH BASEU10CA037420 · NCI · UNIVERSITY OF ROCHESTER · PI MORROW, GARY R · 1985 to 2014
$21.1M
Cancer Control Research Training Curriculum (R25T)R25CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI JANELSINS, MICHELLE C, MORROW, GARY R · 2004 to 2018
$6.7M
Clinical and Translational Cancer Control Research Training ProgramT32CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, Gary R Morrow · 2019 to 2026
$2.7M
Clinical and Translational Approaches to Cognitive Impairments in CancerDP2CA195765 · NCI · UNIVERSITY OF ROCHESTER · PI JANELSINS, MICHELLE C · 2014 to 2014
$2.3M
The Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy, Inflammation, and Interoceptive Brain CircuitryK07CA221931 · NCI · UNIVERSITY OF ROCHESTER · PI KLECKNER, IAN ROBERT · 2018 to 2022
$795k
National Institute of Health K07CA221931National Institute of Health R25 CA1026185NCI NIH HHS DP2 CA195765NCI NIH HHS K07 CA221931NCI NIH HHS R25 CA102618NCI NIH HHS T32 CA102618NCI NIH HHS U10 CA037420NCI NIH HHS U10CA037420NCI NIH HHS UG1 CA189961
6 · The paper itself

Abstract

purposeTo assess the impact of obesity on cancer-related fatigue (CRF) in patients with breast cancer, through a secondary analysis of a large, longitudinal, nationwide study of breast cancer patients beginning chemotherapy.

methodsAll patients (N = 565; aged 53 ± 10.6) with breast cancer completed the multidimensional fatigue symptom inventory and the symptom inventory to measure CRF symptoms at baseline, post-chemotherapy, and 6 months post-chemotherapy. Height and weight at baseline were used to categorize subjects based on body mass index (BMI): obese (≥ 30.0 kg/m

resultsAt baseline, the obese had significantly higher CRF symptoms than the normal weight subjects for both the Multidimensional fatigue symptom inventory (MFSI) total (obese = 11.2 vs normal weight = 6.3; p = 0.03) and Symptom Inventory (SI) (obese = 3.5 vs normal weight = 2.9; p = 0.03). Significantly higher SI fatigue scores persisted at post-chemotherapy for the obese (obese = 5.0 vs normal weight = 4.4; p = 0.02). At 6 months post-chemotherapy, the obese patients still had significantly higher SI fatigue scores (obese = 3.5 vs normal weight = 3.0; p = 0.05).

conclusionObese patients suffered greater CRF from pre-chemotherapy through 6 months post-chemotherapy. Recommendations for weight loss or weight maintenance may impact CRF levels in obese breast cancer patients before and after chemotherapy.

Indexed as

Body Mass IndexAdultAgedBreast NeoplasmsChild, PreschoolFatigueFemaleHumansLongitudinal StudiesMiddle AgedNeoplasm StagingObesityBreast cancerCancer-related fatigueChemotherapyObesity

Identifiers

PMID31267279
PMCPMC7243469
OpenAlexW2955211950

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.