Evidence map›Paper›PMID 31267223›Full record

SynthesisEuropean journal of pediatrics2019

Topical application of coconut oil to the skin of preterm infants: a systematic review.

Sameer Shivaji Pupala, Shripada Rao, Tobias Strunk, Sanjay Patole

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 7 pooled it
8.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 7 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Skin care interventions in infants for preventing eczema and food allergy.The Cochrane database of systematic reviews · 2022
    Pooled it
  5. Pooled it
  6. Topical emollient for preventing infection in preterm infants.The Cochrane database of systematic reviews · 2021
    Pooled it
  7. Skin care interventions in infants for preventing eczema and food allergy.The Cochrane database of systematic reviews · 2021
    Pooled it
  8. Trial
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Neonatal sepsis and the skin microbiome.Journal of perinatology : official journal of the California Perinatal Association · 2022
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Sameer Shivaji PupalaNeonatal Directorate, King Edward Memorial Hospital for Women and Perth Children's Hospital, Perth, WA, Australia. sameer.pupala@health.wa.gov.au.
Shripada RaoNeonatal Directorate, King Edward Memorial Hospital for Women and Perth Children's Hospital, Perth, WA, Australia.
Tobias StrunkNeonatal Directorate, King Edward Memorial Hospital for Women and Perth Children's Hospital, Perth, WA, Australia.
Sanjay PatoleNeonatal Directorate, King Edward Memorial Hospital for Women and Perth Children's Hospital, Perth, WA, Australia.
King Edward Memorial Hospital · AUPerth Children's HospitalPrincess Margaret Hospital for Children · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preterm infants are at risk of increased trans-epidermal water loss and infections due to epidermal immaturity. The emollient and anti-infective properties of coconut oil make it a potentially beneficial topical agent for this population. We aimed to systematically review randomised trials assessing the effects of topical coconut oil in preterm infants. Medline, EMBASE, Cochrane Central Register of Controlled Trials and CINAHL were searched. Seven trials (n = 727 infants) were included. The majority of trials included relatively mature infants (gestation > 32 weeks, birth weight > 1200 g). The duration of intervention (5-31 days) and outcomes of interest varied among included studies. Meta-analysis using random effects model found significantly lower incidence of hospital-acquired blood stream infections (HABSI) in the coconut oil group (11/164 vs 32/166; relative risk 0.35, 95% confidence interval 0.18, 0.67, p = 0.001; I

Indexed as

Administration, CutaneousAnti-Infective AgentsCoconut OilDehydrationEmollientsHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesNeonatal SepsisRandomized Controlled Trials as TopicSkin CareTreatment OutcomeWeight GainAnti-Infective AgentsCoconut OilEmollientsCoconut oilPreterm infantSepsisSkinTopicalTrans-epidermal water loss

Identifiers

PMID31267223
OpenAlexW2954322983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.