Trial reportInternational journal of colorectal disease2019
Prospective randomized clinical trial of uncomplicated right-sided colonic diverticulitis: antibiotics versus no antibiotics.
Trial report in International journal of colorectal disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02314013 (Prospective Randomized Clinical Trial for the Management of Uncomplicated Diverticulitis in Right Colon; Non-antibiotics Versus Antibiotics), which is not on this map. Cited by 18 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective Randomized Clinical Trial for the Management of Uncomplicated Diverticulitis in Right Colon; Non-antibiotics Versus Antibiotics
Who cites it
18 citing papers in PubMed, 7 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Systematic review and meta-analysis of the management of acute uncomplicated diverticulitis: time to change traditional practice.International journal of colorectal disease · 2024Pooled it
- Antibiotics vs observational therapy in acute uncomplicated diverticulitis, a systemic review and meta-analysis.International journal of colorectal disease · 2023Pooled it
- The outcomes of right-sided and left-sided colonic diverticulitis following non-operative management: a systematic review and meta-analysis.World journal of emergency surgery : WJES · 2022Pooled it
- Antibiotics for uncomplicated diverticulitis.The Cochrane database of systematic reviews · 2022Pooled it
- Recurrence of Uncomplicated Diverticulitis: A Meta-Analysis.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Conservative treatment of uncomplicated right-sided diverticulitis: a systematic review and meta-analysis.International journal of colorectal disease · 2021Pooled it
- 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting.World journal of emergency surgery : WJES · 2020Guideline
- Evidence-based clinical practice guidelines for diagnosis and medical management of acute colonic diverticulitis developed by the Korean Association for the Study of Intestinal Diseases (KASID).Intestinal research · 2026Review
- Review
- Article
- Diagnosis and management of acute colonic diverticulitis: results of a survey among Korean gastroenterologists.The Korean journal of internal medicine · 2023Article
- Source control in emergency general surgery: WSES, GAIS, SIS-E, SIS-A guidelines.World journal of emergency surgery : WJES · 2023Review
- Right-sided diverticulitis in a Western population.International journal of colorectal disease · 2022Article
- Management and long-term outcomes of acute right colonic diverticulitis and risk factors of recurrence.BMC surgery · 2022Article
- Right sided diverticulitis in western countries: A review.World journal of gastrointestinal surgery · 2021Article
- WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections.World journal of emergency surgery : WJES · 2021Review
- Routine antibiotics may not be needed to treat uncomplicated right diverticulitis: A retrospective cohort study.PloS one · 2021Article
- Antibiotics in Uncomplicated Diverticulitis: Are we Aligning With the Evidence? A Retrospective Two-Centre Study.ANZ journal of surgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAntibiotics are widely used in the treatment of uncomplicated left-sided colonic diverticulitis. In Asian countries, however, right-sided colonic diverticulitis is more common than left-sided colonic diverticulitis. The aim of the present study was to evaluate the need for antibiotics in the treatment of uncomplicated right-sided colonic diverticulitis in an Asian population.
methodsPatients were randomized to two management strategies: antibiotics and no antibiotics. At 4-6 weeks after discharge, the patients in both groups underwent computed tomography or were contacted by phone to confirm the effectiveness of the treatment. The primary end point was the treatment failure rate of the initial treatment, and secondary end points were the length of hospital stay and total admission costs.
resultsPatients were randomized to treatment with (61 patients) or without (64 patients) antibiotics. The rates of treatment failure in the antibiotics and no antibiotics groups were 1.7% and 4.6%, respectively, with no significant difference (P = 0.619). There was also no significant difference in the length of hospital stay between the groups (P = 0.983). Total admission costs were lower in the no antibiotics group than in the antibiotics group (US$1004.70 vs US$1112.40, respectively, P = 0.037).
conclusionConservative management of uncomplicated right-sided colonic diverticulitis without antibiotics shows similar treatment failure rates and length of hospital stay, and is associated with lower hospital costs, compared with standard antibiotic treatment. Therefore, conservative management can be considered as a safe treatment option.
trial registrationClinicalTrial.gov No. NCT02314013.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.