ArticleJournal of experimental botany2019
The bHLH family member ZmPTF1 regulates drought tolerance in maize by promoting root development and abscisic acid synthesis.
Article in Journal of experimental botany, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 2 of them syntheses that pooled it.
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74 citing papers in PubMed, 2 syntheses or guidelines pooled it, 147 citations in OpenAlex.
- Meta-Quantitative Trait Loci Analysis and Candidate Gene Mining for Drought Tolerance-Associated Traits in Maize (International journal of molecular sciences · 2024Pooled it
- Abiotic Stress in Crop Production.International journal of molecular sciences · 2023Pooled it
- Heterologous expression of DobHLH25 from Dendrobium officinale enhances drought tolerance in Arabidopsis.Functional & integrative genomics · 2026Article
- Genome-Wide Identification and Characterization of bHLH Family inLife (Basel, Switzerland) · 2026Article
- Transcription factor SlbHLH70 enhances drought tolerance in tomato.Horticulture research · 2026Article
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- Molecular and Genetic Regulation of Crop Root System Architecture in Drought Resilience.Plants (Basel, Switzerland) · 2026Review
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- Drought stress inFrontiers in plant science · 2026Review
- All roads lead to Rome: integrated physiological and transcriptomic analysis of cacao drought response reveals different ways to achieve tolerance in two hybrid clones.Frontiers in plant science · 2026Article
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- Genome-wide identification and characterization of theFrontiers in plant science · 2026Article
- Responses of maize roots, rhizosphere enzyme kinetics and prokaryote diversity to alternating precipitation: insights from a three-year field study.Annals of botany · 2025Article
- bHLH Transcription Factors in Cereal Crops: Diverse Functions in Regulating Growth, Development and Stress Responses.International journal of molecular sciences · 2025Review
- A maize landrace introgression library reveals a negative effect of root-to-shoot ratio on water-use efficiency.The plant genome · 2025Article
- Overview of RING gene family in maize (Zea mays L.): ZmRING-93 enhances drought tolerance in transgenic Arabidopsis.BMC plant biology · 2025Article
- Drought stress memory in maize: understanding and harnessing the past for future resilience.Plant cell reports · 2025Review
- A bHLH transcription factor RrUNE12 regulates salt tolerance and promotes ascorbate synthesis.Plant cell reports · 2025Article
- Genome- and Transcriptome-Wide Characterization and Expression Analyses of bHLH Transcription Factor Family Reveal Their Relevance to Salt Stress Response in Tomato.Plants (Basel, Switzerland) · 2025Article
14 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Drought stress is the most important environmental stress limiting maize production. ZmPTF1, a phosphate starvation-induced basic helix-loop-helix (bHLH) transcription factor, contributes to root development and low-phosphate tolerance in maize. Here, ZmPTF1 expression, drought tolerance, and the underlying mechanisms were studied by using maize ZmPTF1 overexpression lines and mutants. ZmPTF1 was found to be a positive regulator of root development, ABA synthesis, signalling pathways, and drought tolerance. ZmPTF1 was also found to bind to the G-box element within the promoter of 9-cis-epoxycarotenoid dioxygenase (NCED), C-repeat-binding factor (CBF4), ATAF2/NAC081, NAC30, and other transcription factors, and to act as a positive regulator of the expression of those genes. The dramatically upregulated NCEDs led to increased abscisic acid (ABA) synthesis and activation of the ABA signalling pathway. The up-regulated transcription factors hierarchically regulate the expression of genes involved in root development, stress responses, and modifications of transcriptional regulation. The improved root system, increased ABA content, and activated ABA-, CBF4-, ATAF2-, and NAC30-mediated stress responses increased the drought tolerance of the ZmPTF1 overexpression lines, while the mutants showed opposite trends. This study describes a useful gene for transgenic breeding and helps us understand the role of a bHLH protein in plant root development and stress responses.
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