Evidence map›Paper›PMID 31266950›Full record

ArticleNature communications2019

Fas signaling-mediated T

Yingying Shen, Zhengbo Song, Xinliang Lu, Zeyu Ma, Chaojie Lu, Bei Zhang, Yinghu Chen, Meng Duan, Lionel Apetoh, Xu Li and 6 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Go to the scene: TJournal for immunotherapy of cancer · 2025
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  8. CD4Trends in cancer · 2024
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. T cells in health and disease.Signal transduction and targeted therapy · 2023
    Review
  16. The Dichotomy of Interleukin-9 Function in the Tumor Microenvironment.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2023
    Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 2 countries.

Yingying ShenInstitute of Immunology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China.
Zhengbo SongDepartment of Medical Oncology, Zhejiang Cancer Hospital, 310022, Hangzhou, China.
Xinliang LuInstitute of Immunology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China.
Zeyu MaInstitute of Immunology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China.
Chaojie LuInstitute of Immunology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China.
Bei ZhangInstitute of Immunology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China.
Yinghu ChenDivision of Infection Disease, Zhejiang Key Laboratory for Neonatal Diseases, Children's Hospital, Zhejiang University School of Medicine, 310006, Hangzhou, China.
Meng DuanChronic Disease Research Institute, School of Public Health, School of Medicine, Zhejiang University, 310058, Hangzhou, China.
Lionel ApetohINSERM, U866, Dijon, France.ORCID http://orcid.org/0000-0002-2774-438X
Xu LiSchool of Life Science, Westlake University, 310024, Hangzhou, China.
Jufeng GuoDepartment of Breast Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, 310006, Hangzhou, China.
Ying MiaoClinical Trial Center, Qingdao Municipal Hospital, 266011, Qingdao, China.
Gensheng ZhangDepartment of Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, 310009, Hangzhou, China.
Diya YangXinyuan Institute of Medicine and Biotechnology, School of Life Sciences, Zhejiang Sci-Tech University, 310018, Hangzhou, China.
Zhijian CaiInstitute of Immunology and Department of Orthopaedics of the Second Affiliated Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China. caizj@zju.edu.cn.
Jianli WangInstitute of Immunology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China. jlwang@zju.edu.cn.
First Affiliated Hospital Zhejiang University · CNSecond Affiliated Hospital of Zhejiang University · CNChildren's Hospital of Zhejiang University · CNHangzhou First People's Hospital · CNInserm · FRQingdao University · CNWestlake University · CNZhejiang Cancer Hospital · CNZhejiang Sci-Tech University · CNZhejiang University · CN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 31670877
6 · The paper itself

Abstract

Fas induces apoptosis in activated T cell to maintain immune homeostasis, but the effects of non-apoptotic Fas signaling on T cells remain unclear. Here we show that Fas promotes T

Indexed as

Cell DifferentiationSignal TransductionAnimalsCytokinesfas ReceptorFemaleHumansInflammatory Bowel DiseasesMiceMice, Inbred BALB CMice, Inbred C57BLMice, NudeNeoplasmsNFATC Transcription FactorsNF-kappa Bp38 Mitogen-Activated Protein KinasesCytokinesfas ReceptorNFATC Transcription FactorsNF-kappa Bp38 Mitogen-Activated Protein KinasesProtein Kinase C beta

Identifiers

PMID31266950
PMCPMC6606754
OpenAlexW2953956528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.