Evidence map›Paper›PMID 31266877›Full record

ArticlemBio2019

Allergic Airway Disease Prevents Lethal Synergy of Influenza A Virus-Streptococcus pneumoniae Coinfection.

Sean Roberts, Sharon L Salmon, Donald J Steiner, Clare M Williams, Dennis W Metzger, Yoichi Furuya

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The role of innate immune system in respiratory viral infection related asthma.Frontiers in cellular and infection microbiology · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Influenza in High-Risk Hosts-Lessons Learned from Animal Models.Cold Spring Harbor perspectives in medicine · 2020
    Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sean RobertsDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA.
Sharon L SalmonDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA.
Donald J SteinerDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA.
Clare M WilliamsDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA.
Dennis W MetzgerDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA.
Yoichi FuruyaDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA furuyay@amc.edu.
Albany Medical Center Hospital · US

Funding

ILC2-Mediated Protection from Acute Lung InfectionR01HL140496 · NHLBI · ALBANY MEDICAL COLLEGE · PI METZGER, DENNIS W · 2018 to 2021
$1.9M
NHLBI NIH HHS R01 HL140496
6 · The paper itself

Abstract

Fatal outcomes following influenza infection are often associated with secondary bacterial infections. Allergic airway disease (AAD) is known to influence severe complications from respiratory infections, and yet the mechanistic effect of AAD on influenza virus-

Indexed as

Disease SusceptibilityAnimalsAsthmaCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCoinfectionDisease Models, AnimalHumansInfluenza A virusInfluenza, HumanInterferon-gammaMice, Inbred BALB CMice, Inbred C57BLPneumococcal InfectionsStreptococcus pneumoniaeSurvival AnalysisInterferon-gammaTransforming Growth Factor betacoinfectioninfluenzainterferon gammaStreptococcus pneumoniae

Identifiers

PMID31266877
PMCPMC6606812
OpenAlexW2956108627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.