ArticlemBio2019
New Insights into the Intrinsic and Extrinsic Factors That Shape the Human Skin Microbiome.
Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05427760 (Effect of Using Oxygen on the Diaper Dermatitis in Infants), which is not on this map. Cited by 108 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Using Oxygen on the Diaper Dermatitis in Infants
Who cites it
108 citing papers in PubMed.
- Efficacy and Safety of Epidermidibacterium Keratini EPI-7 Derived Postbiotics in Skin Aging: A Prospective Clinical Study.International journal of molecular sciences · 2023Trial
- Age-adjusted machine learning identifies facial skin microbes associated with skin quality among Korean women.mSystems · 2026Article
- The Human Microbiome in Airborne Particulate Matter-Associated Aging-Related Chronic Diseases: An Evidence-Stratified Review.Environment & health (Washington, D.C.) · 2026Review
- Stability of the skin microbiome during short-term in situ and in vitro conditions: Foundational support for the potential to trace skin sites and identify individuals.International journal of legal medicine · 2026Article
- Interaction between tick and host microbiotas: a four-step waltz.Parasites & vectors · 2026Review
- Bacterial porphyrins in healthy skin: Microbiota components impact melanogenesis and age-related processes leading to Porphyr'ageing.International journal of cosmetic science · 2026Article
- In-vivo pilot study to assess a new plant-based cosmetic formulation containing Ziziphus joazeiro bark extract and Apium graveolens seed extract for the improvement of dandruff while enhancing scalp microbiome balance and barrier function in subjects with oily to dry sensitive scalps.International journal of cosmetic science · 2026Article
- The human skin microbiome remains unchanged after 24 h of sunscreen application.Applied and environmental microbiology · 2026Article
- Article
- Maintaining microbiota across diverse symbiotic organs inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Profiling skin microbiota in an underrepresented population: Indonesian children with atopic dermatitis and controls.Frontiers in medicine · 2026Article
- Age‑Related Remodeling of the Skin Microbiome in Healthy Women: Site‑Specific Patterns Between Sebaceous and Dry Skin Regions.Clinical, cosmetic and investigational dermatology · 2026Article
- Article
- Dye-based qPCR assays for the separate quantification of total bacterial, fungal, arthropod, and plant DNA.PloS one · 2026Article
- Skin microbiome and cutaneous aging mechanisms and clinical implications.Frontiers in microbiology · 2026Review
- The Skin Microbiome and Bioactive Compounds: Mechanisms of Modulation, Dysbiosis, and Dermatological Implications.Molecules (Basel, Switzerland) · 2025Review
- Case Study on Shifts in Human Skin Microbiome During Antarctica Expeditions.Microorganisms · 2025Article
- Exploring the Impact of Skin Care Routines on the Skin Microbiome and Possible Skin Disease Risk-A Pilot Study.Biomedicines · 2025Article
- High-throughput sequencing to analyze changes in the human scalp microbiome during the use of a shampoo.BMC microbiology · 2025Article
- Chronological age estimation from human microbiomes with transformer-based Robust Principal Component Analysis.Communications biology · 2025Article
48 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite recognition that biogeography and individuality shape the function and composition of the human skin microbiome, we know little about how extrinsic and intrinsic host factors influence its composition. To explore the contributions of these factors to skin microbiome variation, we profiled the bacterial microbiomes of 495 North American subjects (ages, 9 to 78 years) at four skin surfaces plus the oral epithelium using 16S rRNA gene amplicon sequencing. We collected subject metadata, including host physiological parameters, through standardized questionnaires and noninvasive biophysical methods. Using a combination of statistical modeling tools, we found that demographic, lifestyle, and physiological factors collectively explained 12 to 20% of the variability in microbiome composition. The influence of health factors was strongest on the oral microbiome. Associations between host factors and the skin microbiome were generally dominated by operational taxonomic units (OTUs) affiliated with the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.