Evidence map›Paper›PMID 31266821›Full record

ArticleRNA (New York, N.Y.)2019

Maximilian Krause, Adnan M Niazi, Kornel Labun, Yamila N Torres Cleuren, Florian S Müller, Eivind Valen

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 111 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Single-molecule mbioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Extended poly(A) tails are a shared feature of herpesvirus mRNAs.bioRxiv : the preprint server for biology · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maximilian Krause *Computational Biology Unit, Department of Informatics, University of Bergen, 5008 Bergen, Norway.ORCID 0000-0002-7715-1160
Adnan M Niazi *Computational Biology Unit, Department of Informatics, University of Bergen, 5008 Bergen, Norway.ORCID 0000-0001-6955-2506
Kornel LabunComputational Biology Unit, Department of Informatics, University of Bergen, 5008 Bergen, Norway.ORCID 0000-0002-1262-2611
Yamila N Torres CleurenComputational Biology Unit, Department of Informatics, University of Bergen, 5008 Bergen, Norway.ORCID 0000-0003-2218-7243
Florian S MüllerComputational Biology Unit, Department of Informatics, University of Bergen, 5008 Bergen, Norway.ORCID 0000-0003-0193-7789
Eivind ValenComputational Biology Unit, Department of Informatics, University of Bergen, 5008 Bergen, Norway.ORCID 0000-0003-1840-6108
University of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyadenylation at the 3'-end is a major regulator of messenger RNA and its length is known to affect nuclear export, stability, and translation, among others. Only recently have strategies emerged that allow for genome-wide poly(A) length assessment. These methods identify genes connected to poly(A) tail measurements indirectly by short-read alignment to genetic 3'-ends. Concurrently, Oxford Nanopore Technologies (ONT) established full-length isoform-specific RNA sequencing containing the entire poly(A) tail. However, assessing poly(A) length through base-calling has so far not been possible due to the inability to resolve long homopolymeric stretches in ONT sequencing. Here we present

Indexed as

NanoporesPoly APolyadenylationPoly TSequence Analysis, DNASequence Analysis, RNAPoly APoly TcDNAnanopore sequencingpoly(A) tailR package

Identifiers

PMID31266821
PMCPMC6800471
OpenAlexW2953562574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.