Evidence map›Paper›PMID 31266809›Full record

ArticleThe Journal of biological chemistry2019

Phosphatidylinositol 4,5-bisphosphate (PIP

Maiwase Tembo, Katherine L Wozniak, Rachel E Bainbridge, Anne E Carlson

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. PIPbioRxiv : the preprint server for biology · 2026
    Article
  3. Pacemaking in the lymphatic system.The Journal of physiology · 2026
    Review
  4. Review
  5. Allosteric coupling between PIPProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Review
  8. Interplay of CaThe Journal of physiology · 2026
    Article
  9. Article
  10. Article
  11. Calcium-activated chloride channel TMEM16A opens via pi-helical transition in transmembrane segment 4.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Article
  13. Article
  14. Niclosamide potentiates TMEM16A and induces vasoconstriction.The Journal of general physiology · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maiwase TemboDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260.
Katherine L WozniakDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260.
Rachel E BainbridgeDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260.
Anne E CarlsonDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260. Electronic address: acarlson@pitt.edu.
University of Pittsburgh · US

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2008 to 2022
$13.4M
Signaling Mechanisms of TMEM16a RegulationR01GM125638 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CARLSON, ANNE E · 2018 to 2022
$1.6M
NIDDK NIH HHS P30 DK079307NIGMS NIH HHS R01 GM125638
6 · The paper itself

Abstract

Transmembrane member 16A (TMEM16A) is a widely expressed Ca

Indexed as

Calcium SignalingIon Channel GatingMembrane PotentialsAnimalsCalciumChloride ChannelsPhosphatidylinositol 4,5-DiphosphateXenopus laevisCalciumChloride ChannelsPhosphatidylinositol 4,5-DiphosphatexANO2 protein, Xenopusanion channelcalciumchloride channeloocytepatch clampphospholipidsignal transductiontransmembrane member 16A (TMEM16A)Xenopus

Identifiers

PMID31266809
PMCPMC6699839
OpenAlexW2953775435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.