Evidence map›Paper›PMID 31266526›Full record

ArticleParticle and fibre toxicology2019

Developmental programming of obesity by maternal exposure to concentrated ambient PM

Yanyi Xu, Wanjun Wang, Minjie Chen, Ji Zhou, Xingke Huang, Shimin Tao, Bin Pan, Zhouzhou Li, Xiaoyun Xie, Weihua Li and 2 more

Open access · goldAbstract read
In one paragraph

Article in Particle and fibre toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
6.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Exposure to PMInternational journal of environmental research and public health · 2021
    Pooled it
  3. Maternal PMReproductive toxicology (Elmsford, N.Y.) · 2026
    Article
  4. Review
  5. Article
  6. Timing determines programming of energy homeostasis by maternal PMEnvironmental pollution (Barking, Essex : 1987) · 2024
    Article
  7. PMHeliyon · 2024
    Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Yanyi XuDepartment of Environmental Health, School of Public Health, Fudan University, 130 Dong'an Rd, Shanghai, 200032, China. yanyi_xu@fudan.edu.cn.
Wanjun WangDepartment of Environmental Health, School of Public Health, Fudan University, 130 Dong'an Rd, Shanghai, 200032, China.
Minjie ChenDepartment of Medicine Cardiology Division, University of Maryland School of Medicine, 20 Penn St. HSFII S005, Baltimore, MD, 21201, USA.
Ji ZhouShanghai Key Laboratory of Meteorology and Health, Shanghai Meteorological Service, Shanghai, China.
Xingke HuangDepartment of Environmental Health, School of Public Health, Fudan University, 130 Dong'an Rd, Shanghai, 200032, China.
Shimin TaoNHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Fudan University, Shanghai, China.
Bin PanDepartment of Environmental Health, School of Public Health, Fudan University, 130 Dong'an Rd, Shanghai, 200032, China.
Zhouzhou LiDepartment of Environmental Health, School of Public Health, Fudan University, 130 Dong'an Rd, Shanghai, 200032, China.
Xiaoyun XieDepartment of Interventional & Vascular Surgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Weihua LiNHC Key Laboratory of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Fudan University, Shanghai, China.
Haidong KanDepartment of Environmental Health, School of Public Health, Fudan University, 130 Dong'an Rd, Shanghai, 200032, China.
Zhekang YingDepartment of Medicine Cardiology Division, University of Maryland School of Medicine, 20 Penn St. HSFII S005, Baltimore, MD, 21201, USA. yingzhekang@hotmail.com.
Fudan University · CNUniversity of Maryland, Baltimore · USShanghai Institute of Planned Parenthood Research · CNShanghai Meteorological Bureau · CNTongji University · CN

Funding

Hypothalamic Inflammation and PM2.5 Exposure-Induced Insulin ResistanceR01ES024516 · NIEHS · UNIVERSITY OF MARYLAND BALTIMORE · PI YING, ZHEKANG · 2014 to 2018
$1.5M
American Heart Association-American Stroke Association 13SDG17070131NIEHS NIH HHS R01 ES024516NIH HHS R01ES024516
6 · The paper itself

Abstract

backgroundObesity is an uncontrolled global epidemic and one of the leading global public health challenges. Maternal exposure to ambient fine particulate matter (PM

resultsOur data show that the pre-conceptional but not gestational exposure to CAP was sufficient to cause male but not female offspring's low birth weight, accelerated postnatal weight gain, and increased adulthood adiposity. These adverse developmental traits were transmitted into the F

conclusionsThe present study identified a pre-conceptional window for the adverse programming of adiposity by maternal exposure to PM

Indexed as

AdiposityAir PollutantsMaternal ExposureObesityParticulate MatterPrenatal Exposure Delayed EffectsAnimalsDisease Models, AnimalFemaleGene Expression Regulation, DevelopmentalGenetic Predisposition to DiseaseMaleMiceMice, Inbred C57BLParticle SizePregnancyAir PollutantsParticulate MatterCross-generational transmissionDevelopmental programmingMaternal exposureObesityPM2.5

Identifiers

PMID31266526
PMCPMC6604135
OpenAlexW2953969530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.