Evidence map›Paper›PMID 31266424›Full record

ArticleProceedings. Biological sciences2019

Intraspecific sequence and gene expression variation contribute little to venom diversity in sidewinder rattlesnakes ( Crotalus cerastes).

Rhett M Rautsaw, Erich P Hofmann, Mark J Margres, Matthew L Holding, Jason L Strickland, Andrew J Mason, Darin R Rokyta, Christopher L Parkinson

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings. Biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Article
  7. Venom phenotype conservation suggests integrated specialization in a lizard-eating snake.Toxicon : official journal of the International Society on Toxinology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rhett M Rautsaw1 Department of Biological Sciences, Clemson University , Clemson, SC 29634 , USA.
Erich P Hofmann1 Department of Biological Sciences, Clemson University , Clemson, SC 29634 , USA.
Mark J Margres1 Department of Biological Sciences, Clemson University , Clemson, SC 29634 , USA.
Matthew L Holding1 Department of Biological Sciences, Clemson University , Clemson, SC 29634 , USA.
Jason L Strickland1 Department of Biological Sciences, Clemson University , Clemson, SC 29634 , USA.
Andrew J Mason1 Department of Biological Sciences, Clemson University , Clemson, SC 29634 , USA.
Darin R Rokyta3 Department of Biological Science, Florida State University , Tallahassee, FL 32306 , USA.
Christopher L Parkinson1 Department of Biological Sciences, Clemson University , Clemson, SC 29634 , USA.
Clemson University · USFlorida State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traits can evolve rapidly through changes in gene expression or protein-coding sequences. However, these forms of genetic variation can be correlated and changes to one can influence the other. As a result, we might expect traits lacking differential expression to preferentially evolve through changes in protein sequences or morphological adaptation. Given the lack of differential expression across the distribution of sidewinder rattlesnakes ( Crotalus cerastes), we tested this hypothesis by comparing the coding regions of genes expressed in the venom gland transcriptomes and fang morphology. We calculated Tajima's D and F

Indexed as

Gene ExpressionAmino Acid SequenceAnimalsCrotalid VenomsCrotalusPhenotypePhylogeographyToothTranscriptomeCrotalid Venomsbalancing selectionecological specialization theorygenetic differentiationSNPsstabilizing selectiontranscriptomics

Identifiers

PMID31266424
PMCPMC6650705
OpenAlexW2955923426

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.