Evidence map›Paper›PMID 31266389›Full record

ArticleJournal of the American Heart Association2019

Windkessel Measures Derived From Pressure Waveforms Only: The Framingham Heart Study.

Vira Behnam, Jian Rong, Martin G Larson, John D Gotal, Emelia J Benjamin, Naomi M Hamburg, Ramachandran S Vasan, Gary F Mitchell

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The modified arterial reservoir: An update with consideration of asymptotic pressure (Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vira Behnam1 Cardiovascular Engineering, Inc. Norwood MA.
Jian Rong2 Boston University and NHLBI's Framingham Study Framingham MA.
Martin G Larson2 Boston University and NHLBI's Framingham Study Framingham MA.
John D Gotal1 Cardiovascular Engineering, Inc. Norwood MA.
Emelia J Benjamin2 Boston University and NHLBI's Framingham Study Framingham MA.
Naomi M Hamburg6 Evans Department of Medicine Boston University School of Medicine Boston MA.
Ramachandran S Vasan2 Boston University and NHLBI's Framingham Study Framingham MA.
Gary F Mitchell1 Cardiovascular Engineering, Inc. Norwood MA.

Funding

Vascular Stiffness as a Precursor of Hypertension in a Middle-aged CohortR01HL126136 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MITCHELL, GARY FRANK, RAMACHANDRAN, VASAN S · 2015 to 2018
$2.6M
Aortic Dysfunction, Pulsatile Stress and Target Organ Damage in FraminghamR01HL107385 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MITCHELL, GARY FRANK, RAMACHANDRAN, VASAN S · 2011 to 2014
$2.6M
Vascular Function in the Framingham Third GenerationR01HL070100 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BENJAMIN, EMELIA J. · 2002 to 2005
$2.4M
ENDOTHELIAL VASAMOTOR FUNCTION IN THE FRAMINGHAM STUDYR01HL060040 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BENJAMIN, EMELIA J. · 1999 to 2002
$595k
NHLBI NIH HHS R01 HL060040NHLBI NIH HHS R01 HL070100NHLBI NIH HHS R01 HL107385NHLBI NIH HHS R01 HL126136
6 · The paper itself

Abstract

Background Waveform parameters derived from pressure-only Windkessel models are related to cardiovascular disease risk and could be useful for understanding arterial system function. However, prior reports varied in their adjustment for potential confounders. Methods and Results Carotid tonometry waveform data from 2539 participants (mean age 63±11 years, 58% women) of the Framingham Heart Study were used to derive Windkessel measures using pressure and assuming a linear model with fixed diastolic time constant (τ

Indexed as

ManometryPulse Wave AnalysisAgedArterial PressureBlood PressureCarotid ArteriesFemaleHeart FailureHeart RateHumansLongitudinal StudiesMaleMiddle AgedMyocardial InfarctionNonlinear DynamicsProportional Hazards Modelsarterial stiffnesspressure waveform analysisrisk assessmenttauWindkessel

Identifiers

PMID31266389
PMCPMC6662135

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.