ArticleMaterials (Basel, Switzerland)2019
Development and Bone Regeneration Capacity of Premixed Magnesium Phosphate Cement Pastes.
Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Reconstruction of hematopoietic stem cell nichesMaterials today. Bio · 2025Review
- In Vivo Degradation Behaviour and Osteoregenerative Capacity of 3D-Printed Magnesium Phosphate and Calcium Magnesium Phosphate Cement Scaffolds.Materials (Basel, Switzerland) · 2025Article
- Bone filler and adhesive at the same time: in-vitro analysis in a porcine fracture model.BMC musculoskeletal disorders · 2025Article
- A magnesium calcium phosphate-based cement as a bone adhesive: characterization and biomechanical evaluation.BMC musculoskeletal disorders · 2025Article
- Hypermagnesemia- and Hyperphosphatemia-Associated Cardiac Arrest after Injection of a Novel Magnesium-Based Bone Cement in Spinal Surgery.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- In Vivo Investigation of 3D-Printed Calcium Magnesium Phosphate Wedges in Partial Load Defects.Materials (Basel, Switzerland) · 2024Article
- Ready-To-Use and Rapidly Biodegradable Magnesium Phosphate Bone Cement: In Vivo Evaluation in Sheep.Advanced healthcare materials · 2023Article
- Characterization and Biomechanical Study of a Novel Magnesium Potassium Phosphate Cement.Life (Basel, Switzerland) · 2022Article
- Characterization of Tetracalcium Phosphate/Monetite Biocement Modified by Magnesium Pyrophosphate.Materials (Basel, Switzerland) · 2022Article
- Latest Trends in Surface Modification for Dental Implantology: Innovative Developments and Analytical Applications.Pharmaceutics · 2022Review
- Comparison of degradation behavior and osseointegration of 3D powder-printed calcium magnesium phosphate cement scaffolds with alkaline or acid post-treatment.Frontiers in bioengineering and biotechnology · 2022Article
- Magnesium Ammonium Phosphate Composite Cell-Laden Hydrogel Promotes Osteogenesis and AngiogenesisACS omega · 2021Article
- In-Vivo Degradation Behavior and Osseointegration of 3D Powder-Printed Calcium Magnesium Phosphate Cement Scaffolds.Materials (Basel, Switzerland) · 2021Article
- Insitu magnesium calcium phosphate cements formation: From one pot powders precursors synthesis toBioactive materials · 2020Article
- 3D Printing of Bone Grafts for Cleft Alveolar Osteoplasty -Frontiers in bioengineering and biotechnology · 2020Article
- Comprehensive In Vitro Testing of Calcium Phosphate-Based Bioceramics with Orthopedic and Dentistry Applications.Materials (Basel, Switzerland) · 2019Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Magnesium phosphate cements (MPC) have been demonstrated to have a superior bone regeneration capacity due to their good solubility under in vivo conditions. While in the past only aqueous MPC pastes have been applied, the current study describes the fabrication and in vitro/in vivo testing of an oil-based calcium doped magnesium phosphate (CaMgP) cement paste. Premixed oil-based pastes with CaMgP chemistry combine the advantages of conventional MPC such as high mechanical strength and good resorbability with a prolonged shelf-life and an easier clinical handling. The pastes set in an aqueous environment and predominantly form struvite and achieve a compressive strength of ~8-10 MPa after setting. The implantation into a drill-hole defect at the distal femoral condyle of New Zealand white rabbits over a course of 6 and 12 weeks demonstrated good biocompatibility of the materials without the formation of soft connective tissue or any signs of inflammation. In contrast to a hydroxyapatite forming reference paste, the premixed CaMgP pastes showed subsequent degradation and bony regeneration. The CaMgP cement pastes presented herein are promising bone replacement materials with excellent material properties for an improved and facilitated clinical application.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.