Evidence map›Paper›PMID 31265213›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2019

Targeted Gold Nanocluster-Enhanced Radiotherapy of Prostate Cancer.

Dong Luo, Xinning Wang, Sophia Zeng, Gopalakrishnan Ramamurthy, Clemens Burda, James P Basilion

Open access · greenAbstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 118 citations in OpenAlex.

  1. Golden era of radiosensitizers.Frontiers in veterinary science · 2024
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Atomically-precise AuJournal of nanobiotechnology · 2025
    Article
  8. Review
  9. Applications of AuNanomaterials (Basel, Switzerland) · 2024
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Assembling AuJournal of nanobiotechnology · 2024
    Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dong LuoDepartment of Radiology, Case Western Reserve University, Cleveland, OH, 44106, USA.ORCID 0000-0002-9711-2070
Xinning WangDepartment of Radiology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Sophia ZengDepartment of Radiology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Gopalakrishnan RamamurthyDepartment of Radiology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Clemens BurdaDepartment of Chemistry, Case Western Reserve University, Cleveland, OH, 44106, USA.
James P BasilionDepartment of Radiology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Case Western Reserve University · US

Funding

Theranostic gold nanoparticles for imaged-guided radical prostatectomy and PDT ablationR01EB020353 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI BASILION, JAMES PETER · 2016 to 2019
$2.7M
NIBIB NIH HHS R01 EB020353
6 · The paper itself

Abstract

For over a hundred years, X-rays have been a main component of the radiotherapeutic approaches to treat cancer. Yet, to date, no radiosensitizer has been developed to selectively target prostate cancer. Gold has excellent X-ray absorptivity and is used as a radiotherapy enhancing material. In this work, ultrasmall Au

Indexed as

AnimalsCell Line, TumorCell ProliferationGoldHumansImaging, Three-DimensionalLiverMaleMetal NanoparticlesMiceParticle SizeProstatic NeoplasmsTomography, X-Ray ComputedGoldgold nanoclustersprostate cancerPSMAradiosensitizationtargeted radiotherapy

Identifiers

PMID31265213
PMCPMC6707872
OpenAlexW2953874013

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.