ArticleThe Journal of comparative neurology2020
A systematic topographical relationship between mouse lateral posterior thalamic neurons and their visual cortical projection targets.
Article in The Journal of comparative neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Functional ultrasound imaging reveals early pathway-specific reorganization of central visual circuits in a mouse model of Batten disease.Neurobiology of disease · 2026Article
- Excitatory and inhibitory networks diverge following early blindness.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Spatial biases in visual feature representation of mouse dorsal lateral geniculate nucleus boutons.iScience · 2026Article
- The role of transthalamic pathways in perception.Communications biology · 2026Review
- Neurons embedded in loop-like motifs act as central hubs for brain-wide integration.The Journal of physiology · 2026Article
- Exploring Deep Magnetoencephalography via Thalamo-Cortical Sleep Spindles.Human brain mapping · 2025Article
- Article
- Interdigitating Modules for Visual Processing During Locomotion and Rest in Mouse V1.bioRxiv : the preprint server for biology · 2025Article
- Complementary Organization of Mouse Driver and Modulator Cortico-thalamo-cortical Circuits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Article
- Attentional modulation of secondary somatosensory and visual thalamus of mice.bioRxiv : the preprint server for biology · 2024Article
- Transthalamic Pathways for Cortical Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- A Reconsideration of the Core and Matrix Classification of Thalamocortical Projections.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Understanding subcortical projections to the lateral posterior thalamic nucleus and its subregions using retrograde neural tracing.Frontiers in neuroanatomy · 2024Article
- Multi-layered maps of neuropil with segmentation-guided contrastive learning.Nature methods · 2023Article
- Characterization of primary visual cortex input to specific cell types in the superior colliculus.Frontiers in neuroanatomy · 2023Article
- Thalamocortical circuits for the formation of hierarchical pathways in the mammalian visual cortex.Frontiers in neural circuits · 2023Review
- Alexa Fluor 488-conjugated cholera toxin subunit B optimally labels neurons 3-7 days after injection into the rat gastrocnemius muscle.Neural regeneration research · 2022Article
- Brain-wide mapping of inputs to the mouse lateral posterior (LP/Pulvinar) thalamus-anterior cingulate cortex network.The Journal of comparative neurology · 2022Article
- Conserved patterns of functional organization between cortex and thalamus in mice.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
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4 authors.
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Abstract
Higher-order visual thalamus communicates broadly and bi-directionally with primary and extrastriate cortical areas in various mammals. In primates, the pulvinar is a topographically and functionally organized thalamic nucleus that is largely dedicated to visual processing. Still, a more granular connectivity map is needed to understand the role of thalamocortical loops in visually guided behavior. Similarly, the secondary visual thalamic nucleus in mice (the lateral posterior nucleus, LP) has extensive connections with cortex. To resolve the precise connectivity of these circuits, we first mapped mouse visual cortical areas using intrinsic signal optical imaging and then injected fluorescently tagged retrograde tracers (cholera toxin subunit B) into retinotopically-matched locations in various combinations of seven different visual areas. We find that LP neurons representing matched regions in visual space but projecting to different extrastriate areas are found in different topographically organized zones, with few double-labeled cells (~4-6%). In addition, V1 and extrastriate visual areas received input from the ventrolateral part of the laterodorsal nucleus of the thalamus (LDVL). These observations indicate that the thalamus provides topographically organized circuits to each mouse visual area and raise new questions about the contributions from LP and LDVL to cortical activity.
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