Evidence map›Paper›PMID 31264582›Full record

ArticleeLife2019

The Makorin

Hannah Lawson, Edward Vuong, Renee M Miller, Karin Kiontke, David Ha Fitch, Douglas S Portman

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. A gene expression atlas of a juvenile nervous system.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Two intrinsic timing mechanisms set start and end times for dendritic arborization of a nociceptive neuron.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hannah LawsonDepartment of Biology, University of Rochester, Rochester, United States.
Edward VuongDepartment of Biomedical Genetics, University of Rochester, Rochester, United States.
Renee M MillerDepartment of Brain and Cognitive Sciences, University of Rochester, Rochester, United States.
Karin KiontkeCenter for Developmental Genetics, Department of Biology, New York University, New York, United States.
David Ha FitchCenter for Developmental Genetics, Department of Biology, New York University, New York, United States.
Douglas S PortmanDepartment of Biology, University of Rochester, Rochester, United States.ORCID 0000-0003-2686-8839

Funding

University of Rochester Mentoring Environment: Nurturing Training Opportunities in Research (UR-MENTOR)T32GM007356 · NIGMS · UNIVERSITY OF ROCHESTER · PI O'BANION, M. KERRY · 1985 to 2023
$15.1M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Neurogenetic mechanisms of sensory circuit plasticityR01GM130136 · NIGMS · UNIVERSITY OF ROCHESTER · PI PORTMAN, DOUGLAS S · 2018 to 2021
$1.2M
Architecture of a Genetic Network Governing MorphogenesisR01GM100140 · NIGMS · NEW YORK UNIVERSITY · PI FITCH, DAVID H. A. · 2012 to 2015
$1.1M
Genetic and Hormonal Mechanisms of Sex Differences in the Nervous SystemR01GM108885 · NIGMS · UNIVERSITY OF ROCHESTER · PI PORTMAN, DOUGLAS S · 2014 to 2017
$1.1M
National Science Foundation DEB 0922012National Science Foundation IOS 1353075NIGMS NIH HHS R01 GM100140NIGMS NIH HHS R01 GM108885NIGMS NIH HHS R01 GM130136NIGMS NIH HHS T32 GM007356NIH HHS P40 OD010440
6 · The paper itself

Abstract

Sexual maturation must occur on a controlled developmental schedule. In mammals, Makorin3 (

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell DifferentiationGene Expression Regulation, DevelopmentalHumansMicroRNAsMutationNervous SystemRepressor ProteinsRibonucleoproteinsRNA, Long NoncodingSexual MaturationUbiquitin-Protein LigasesCaenorhabditis elegans ProteinsLEP-2 protein, C elegansLIN-28 protein, C elegansMicroRNAsMKRN3 protein, humanRepressor ProteinsRibonucleoproteinsRNA, Long NoncodingUbiquitin-Protein LigasesbehaviorC. elegansdevelopmental biologydevelopmental timingLIN28lncRNAneurosciencereproductive maturationsexual differentiation

Identifiers

PMID31264582
PMCPMC6606027

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.