Evidence map›Paper›PMID 31264500›Full record

ArticleStem cells and development2019

Comparison of Human Tissue Microarray to Human Pericyte Transcriptome Yields Novel Perivascular Cell Markers.

Ching Yun Hsu, Mario Gomez Salazar, Sarah Miller, Carolyn Meyers, Catherine Ding, Winters Hardy, Bruno Péault, Aaron W James

Open access · greenAbstract read
In one paragraph

Article in Stem cells and development, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Differential pericyte marker expression in craniofacial benign and malignant vascular tumors.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2023
    Article
  5. Article
  6. Blood Vessel Resident Human Stem Cells in Health and Disease.Stem cells translational medicine · 2022
    Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ching Yun HsuDepartment of Pathology, Johns Hopkins University, Baltimore, Maryland.
Mario Gomez SalazarCenter for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Sarah MillerDepartment of Pathology, Johns Hopkins University, Baltimore, Maryland.
Carolyn MeyersDepartment of Pathology, Johns Hopkins University, Baltimore, Maryland.
Catherine DingOrthopaedic Hospital Research Center, University of California, Los Angeles, Los Angeles, California.
Winters HardyOrthopaedic Hospital Research Center, University of California, Los Angeles, Los Angeles, California.
Bruno PéaultCenter for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Aaron W JamesDepartment of Pathology, Johns Hopkins University, Baltimore, Maryland.
Johns Hopkins University · USOrthopaedic Hospital · USUniversity of California, Los Angeles · USMRC Centre for Regenerative Medicine · GB

Funding

Direct and indirect contributions of perivascular stem cells to bone healingR01AR070773 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI JAMES, AARON W · 2017 to 2021
$1.4M
NELL-1 isoforms for the systemic treatment of osteoporosisK08AR068316 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JAMES, AARON W · 2015 to 2019
$534k
Role of sensory nerves in cranial bone repairR21DE027922 · NIDCR · JOHNS HOPKINS UNIVERSITY · PI CLEMENS, THOMAS L, JAMES, AARON W · 2018 to 2019
$450k
Medical Research Council G1000816NIAMS NIH HHS K08 AR068316NIAMS NIH HHS R01 AR070773NIDCR NIH HHS R21 DE027922
6 · The paper itself

Abstract

Human perivascular progenitor cells, including pericytes, are well-described multipotent mesenchymal cells giving rise to mesenchymal stem cells in culture. Despite the unique location of pericytes, specific antigens to distinguish human pericytes from other cell types are few. Here, we employed a human tissue microarray (Human Protein Atlas) to identify proteins that are strongly and specifically expressed in a pericytic location within human adipose tissue. Next, these results were cross-referenced with RNA sequencing data from human adipose tissue pericytes, as defined as a fluorescence activated cell sorting (FACS) purified CD146

Indexed as

TranscriptomeAdipose TissueAntigens, CDCells, CulturedFlow CytometryGene Expression ProfilingHumansPericytesProteomeSoftwareTissue Array AnalysisAntigens, CDProteomemesenchymal stem cellpericytepericyte markers

Identifiers

PMID31264500
PMCPMC6751392
OpenAlexW2953599294

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.