Evidence map›Paper›PMID 31264387›Full record

ArticlePhysiological reports2019

Exercise training increases GAD65 expression, restores the depressed GABA

Nilson C Ferreira-Junior, Adriana Ruggeri, Sebastião D Silva, Thais T Zampieri, Alexandre Ceroni, Lisete C Michelini

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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  3. Prenatal LPS leads to increases in RAS expression within the PVN and overactivation of sympathetic outflow in offspring rats.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Nilson C Ferreira-JuniorDepartment of Physiology & Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil.
Adriana RuggeriDepartment of Physiology & Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil.
Sebastião D SilvaDepartment of Physiology & Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil.
Thais T ZampieriDepartment of Physiology & Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil.
Alexandre CeroniDepartment of Physiology & Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil.
Lisete C MicheliniDepartment of Physiology & Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil.ORCID 0000-0003-2978-5406
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GABAergic inhibitory input within the paraventricular hypothalamic nucleus (PVN) plays a key role in restraining sympathetic outflow. Although experimental evidence has shown depressed GABA

Indexed as

Physical ExertionAnimalsBaroreflexBlood PressureGlutamate DecarboxylaseHypertensionIsoenzymesMaleParaventricular Hypothalamic NucleusRatsRats, Inbred SHRRats, WistarReceptors, GABA-ASympathetic Nervous SystemGlutamate Decarboxylaseglutamate decarboxylase 2IsoenzymesReceptors, GABA-AAutonomic nervous systembicucullineexerciseGABAA receptorsglutamic acid decarboxylasehypothalamusspontaneous hypertension

Identifiers

PMID31264387
PMCPMC6603325
OpenAlexW2953653810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.