Observational studyCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2020
Sex differences in procedural and clinical outcomes following rotational atherectomy.
Observational study in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07512206 (AERO CAD), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
AERO CAD: A Prospective, Multi-Center, Single-Arm Study Evaluating the Shockwave C2 Aero Coronary IVL System in Calcified Coronary Artery Disease
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Coronary perforation incidence, outcomes and temporal trends (COPIT): a systematic review and meta-analysis.Open heart · 2022Pooled it
- Breaking Down Barriers … and Calcium: The EMPOWERment of Women With Calcific Coronary Artery Disease.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Treating Women With Calcified Coronary Arteries Using Intravascular Lithotripsy: Primary Results of the EMPOWER CAD Study.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Sex-based Differences in Complications Following Percutaneous Coronary Interventions.Current atherosclerosis reports · 2025Review
- Equity in Modifying Plaque of Women With Undertreated Calcified Coronary Artery Disease: Design and Rationale of EMPOWER CAD study.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- Risk factors of cardiac arrest during a percutaneous coronary intervention performed with rotational atherectomy - analysis based on a Large National Registry.Cardiology journal · 2024Article
- Sex related disparities after complex percutaneous coronary interventions.Frontiers in cardiovascular medicine · 2024Article
- Percutaneous Coronary Interventions in Women.Current atherosclerosis reports · 2023Review
- Sex-Based Differences in Rotational Atherectomy and Long-Term Clinical Outcomes.Journal of clinical medicine · 2023Article
- Sex-specific Inequalities in the Treatment of Severely Calcified Coronary Lesions: A Sub-analysis of the PREPARE-CALC Trial.Interventional cardiology (London, England) · 2023Article
- Outcomes of Complex Percutaneous Cardiac Interventions in Women.US cardiology · 2023Review
- Sex-based Differences in Percutaneous Coronary Intervention Outcomes in Patients with Ischaemic Heart Disease.European cardiology · 2023Review
- Emergency transvenous temporary pacing during rotational atherectomy.Frontiers in cardiovascular medicine · 2023Article
- Coronary Artery Perforations: Glasgow Natural History Study of Covered Stent Coronary Interventions (GNOCCI) Study.Journal of the American Heart Association · 2022Observational
- Sex differences in clinical outcomes after rotational atherectomy of calcified coronary stenoses: from multicenter registry.American journal of cardiovascular disease · 2021Article
- Sex differences in procedural and clinical outcomes following rotational atherectomy.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2020Observational
- SCAI Expert Consensus Statement on Sex-Specific Considerations in Myocardial Revascularization.Journal of the Society for Cardiovascular Angiography & InterventionsArticle
- Sex-Specific Outcomes After Coronary Intravascular Lithotripsy: A Patient-Level Analysis of the Disrupt CAD Studies.Journal of the Society for Cardiovascular Angiography & InterventionsArticle
- Seek First to Understand: Sex-Specific Outcomes of Patients With Calcified Coronary Arteries Treated With Intravascular Lithotripsy.Journal of the Society for Cardiovascular Angiography & InterventionsArticle
- Coronary Intravascular Lithotripsy for Treatment of Severely Calcified Lesions: Long-Term Sex-Specific Outcomes.Journal of the Society for Cardiovascular Angiography & InterventionsArticle
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
aimEvaluate sex differences in procedural net adverse clinical events and long-term outcomes following rotational atherectomy (RA). METHODS AND
resultsFrom August 2010 to 2016, 765 consecutive patients undergoing RA PCI were followed up for a median of 4.7 years. 285 (37%) of subjects were female. Women were older (mean 76 years vs. 72 years; p < .001) and had more urgent procedures (64.6 vs. 47.3%; p < .001). Females received fewer radial procedures (75.1 vs. 85.1%; p < .001) and less intravascular imaging guidance (16.8 vs. 25.0%; p = .008). After propensity score adjustment, the primary endpoint of net adverse cardiac events (net adverse clinical events: all-cause death, myocardial infarction, stroke, target vessel revascularization plus any procedural complication) occurred more often in female patients (15.1 vs. 9.0%; adjusted OR 1.81 95% CI 1.04-3.13; p = .037). This was driven by an increased risk of procedural complications rather than procedural major adverse cardiac events (MACE). Specifically, women were more likely to experience coronary dissection (4.6 vs. 1.3%; p = .008), cardiac tamponade (2.1 vs. 0.4%; p = .046) and significant bleeding (BARC ≥2: 5.3 vs. 2.3). Despite this, overall MACE-free survival was similar between males and females (adjusted HR 1.03; 95% CI 0.80-1.34; p = .81). Procedural complications during RA were associated with almost double the incidence of MACE at long-term follow-up (HR 1.92; 95% CI 1.34-2.77; p < .001).
conclusionWomen may be at greater risk of procedural complications following rotational atherectomy. These include periprocedural bleeding episodes and coronary perforation leading to cardiac tamponade. Despite this, the adjusted overall long-term survival free of major adverse cardiac events was similar between males and females.
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Registered trials
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