ArticleJournal of muscle research and cell motility2019
Effects of exposure to mild hyperbaric oxygen during unloading on muscle properties in rats.
Article in Journal of muscle research and cell motility, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Mild hyperbaric oxygen enhanced the regeneration of the tibialis anterior muscle after the cardiotoxin-induced muscle injury.Biochemistry and biophysics reports · 2026Article
- Microbaric oxygen therapy modulates EEG microstates and spectral power in patients with chronic insomnia disorder.BMC psychiatry · 2026Article
- Article
- Effects of mild hyperbaric oxygen therapy on timing sequence recovery of muscle fatigue in cJournal of exercise science and fitness · 2024Article
- Hyperbaric oxygen therapy for healthy aging: From mechanisms to therapeutics.Redox biology · 2022Review
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1 author at 1 institution in 1 country.
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Abstract
This study investigated the effects of exposure to mild hyperbaric oxygen during unloading on the properties of the soleus muscle in rats, because exposure to mild hyperbaric oxygen enhances oxidative metabolism in cells and tissues. Therefore, exposure to mild hyperbaric oxygen should inhibit the unloading-induced degenerative changes in skeletal muscles. One group of 7-week-old male Wistar rats were unloaded by hindlimb suspension for 2 weeks (HU, n = 12). A second group of age-matched rats were exposed to mild hyperbaric oxygen at 1317 hPa with 40% oxygen for 3 h a day during hindlimb suspension (HU + MHO, n = 12). A third group of age-matched rats without hindlimb suspension and exposure to mild hyperbaric oxygen were assigned as the controls (WR, n = 12). Soleus muscle weight (per body weight), succinate dehydrogenase (SDH) activity, and peroxisome proliferator-activated receptor γ coactivator-1α (Pgc-1α) mRNA levels were lower in the HU and HU + MHO groups than in the WR group, and these were higher in the HU + MHO group than in the HU group. The unloading-induced type shift from type I to type IIA fibers was inhibited by exposure to mild hyperbaric oxygen during unloading. It is concluded that the unloading-induced decrease in soleus muscle weight (per body weight) and type shift from type I to type IIA fibers in the soleus muscle were partially inhibited by exposure to mild hyperbaric oxygen during unloading.
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