ArticleGenome biology and evolution2019
The Genome Sequence of the Anthelmintic-Susceptible New Zealand Haemonchus contortus.
Article in Genome biology and evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
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- Multi-Omic Profiling, Structural Characterization, and Potent Inhibitor Screening of Evasion-Related Proteins of a Parasitic Nematode,Biomedicines · 2023Article
- Time-series transcriptomic profiling of larval exsheathment in a model parasitic nematode of veterinary importance.Frontiers in cell and developmental biology · 2023Article
- Research progress and limitation analysis of RNA interference inFrontiers in veterinary science · 2023Review
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- Selection of Genome-Wide SNPs for Pooled Allelotyping Assays Useful for Population Monitoring.Genome biology and evolution · 2022Article
- Bacterial Diversity Profiling of the New Zealand Parasitic Blowfly Lucilia sericata Based on 16S rRNA Gene Amplicon Sequencing.Microbiology resource announcements · 2021Article
- 16S rRNA Gene Amplicon Profiling of the New Zealand Parasitic Blowfly Calliphora vicina.Microbiology resource announcements · 2021Article
- The complete mitochondrial genome of the New Zealand parasitic blowflyMitochondrial DNA. Part B, Resources · 2021Article
- Characterization of the complete mitochondrial genome of the New Zealand parasitic blowflyMitochondrial DNA. Part B, Resources · 2021Article
- Helminth lipidomics: Technical aspects and future prospects.Current research in parasitology & vector-borne diseases · 2021Review
- Sequencing and Reconstructing Helminth Mitochondrial Genomes Directly from Genomic Next-Generation Sequencing Data.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm.Communications biology · 2020Article
- Characterization of the Complete Mitochondrial Genomes of Two Sibling Species of Parasitic Roundworms,Frontiers in genetics · 2020Article
- The complete mitochondrial genome of the New Zealand parasitic roundwormMitochondrial DNA. Part B, Resources · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Internal parasitic nematodes are a global animal health issue causing drastic losses in livestock. Here, we report a H. contortus representative draft genome to serve as a genetic resource to the scientific community and support future experimental research of molecular mechanisms in related parasites. A de novo hybrid assembly was generated from PCR-free whole genome sequence data, resulting in a chromosome-level assembly that is 465 Mb in size encoding 22,341 genes. The genome sequence presented here is consistent with the genome architecture of the existing Haemonchus species and is a valuable resource for future studies regarding population genetic structures of parasitic nematodes. Additionally, comparative pan-genomics with other species of economically important parasitic nematodes have revealed highly open genomes and strong collinearities within the phylum Nematoda.
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