Evidence map›Paper›PMID 31263784›Full record

ArticleCommunications biology2019

Dual Ca

Changyi Ji, Alec Kittredge, Austin Hopiavuori, Nancy Ward, Shoudeng Chen, Yohta Fukuda, Yu Zhang, Tingting Yang

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Gene Therapy Strategies for the Treatment of Bestrophinopathies.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. A novel variant of autosomal recessive best vitelliform macular dystrophy and management of early-onset complications.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Changyi Ji *Department of Pharmacology and Physiology, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642 USA.
Alec Kittredge *Department of Pharmacology and Physiology, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642 USA.
Austin HopiavuoriDepartment of Pharmacology and Physiology, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642 USA.
Nancy WardDepartment of Pharmacology and Physiology, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642 USA.
Shoudeng Chen2Guangdong Provincial Key Laboratory of Biomedical Imaging, Department of Experimental Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, 519000 Zhuhai, Guangzhou China.
Yohta Fukuda3Division of Advance Pharmaco-Science, Graduate School of Pharmaceutical Science, Osaka University, Yamadaoka 1-6, Suita, Osaka 565-0871 Japan.
Yu ZhangDepartment of Pharmacology and Physiology, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642 USA.
Tingting YangDepartment of Pharmacology and Physiology, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642 USA.
University of Rochester · USFifth Affiliated Hospital of Sun Yat-sen University · CNOsaka University · JP

Funding

User Training and OutreachP30GM124165 · NIGMS · CORNELL UNIVERSITY · PI Nozomi Ando, J Christopher Fromme · 2018 to 2026
$34.2M
Pixel Array Detector for Macromolecular CrystallographyS10OD021527 · OD · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2016 to 2016
$2.0M
Pixel Array Detector for X-ray CrystallographyS10RR029205 · NCRR · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2010 to 2010
$1.8M
Mechanistic Characterization of Calcium-Activated Chloride Channels in Retinal Pigment EpitheliumR01GM127652 · NIGMS · UNIVERSITY OF ROCHESTER · PI YANG, TINGTING · 2018 to 2022
$1.7M
Structure-function Analysis of BestrophinsR00EY025290 · NEI · UNIVERSITY OF ROCHESTER · PI YANG, TINGTING · 2016 to 2018
$747k
Structure-function Analysis of BestrophinsK99EY025290 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI YANG, TINGTING · 2015 to 2015
$106k
NCRR NIH HHS S10 RR029205NEI NIH HHS K99 EY025290NEI NIH HHS R00 EY025290NIGMS NIH HHS P30 GM124165NIGMS NIH HHS R01 GM127652NIH HHS S10 OD021527
6 · The paper itself

Abstract

Mutations of human

Indexed as

Gain of Function MutationBestrophinsCalciumChloride ChannelsCrystallographyHEK293 CellsHumansIon Channel GatingPatch-Clamp TechniquesStructure-Activity RelationshipBEST1 protein, humanBestrophinsCalciumChloride ChannelsChloride channelsHereditary eye diseasePatch clampPermeation and transportX-ray crystallography

Identifiers

PMID31263784
PMCPMC6591409
OpenAlexW2954778081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.