Evidence map›Paper›PMID 31263766›Full record

ArticleACS central science2019

Dynamic and Functional Profiling of Xylan-Degrading Enzymes in

Sybrin P Schröder, Casper de Boer, Nicholas G S McGregor, Rhianna J Rowland, Olga Moroz, Elena Blagova, Jos Reijngoud, Mark Arentshorst, David Osborn, Marc D Morant and 15 more

Open access · diamondAbstract read
In one paragraph

Article in ACS central science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
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  4. Synthesis and Application of Bioactive N-Functionalized Aziridines.Angewandte Chemie (International ed. in English) · 2025
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  7. Structural glycobiology - from enzymes to organelles.Biochemical Society transactions · 2025
    Review
  8. Review
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  10. Article
  11. Microbiology spectrum · 2024
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  16. Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  17. Synthesis of broad-specificity activity-based probes forOrganic & biomolecular chemistry · 2022
    Article
  18. Article
  19. Design, Synthesis and Structural Analysis of Glucocerebrosidase Imaging Agents.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
  20. Xylose-Configured Cyclophellitols as Selective Inhibitors for Glucocerebrosidase.Chembiochem : a European journal of chemical biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 7 institutions in 6 countries.

Sybrin P SchröderLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA Leiden, The Netherlands.
Casper de BoerLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA Leiden, The Netherlands.
Nicholas G S McGregorYork Structural Biology Laboratory, Department of Chemistry, The University of York, York YO10 5DD, U.K.
Rhianna J RowlandYork Structural Biology Laboratory, Department of Chemistry, The University of York, York YO10 5DD, U.K.
Olga MorozYork Structural Biology Laboratory, Department of Chemistry, The University of York, York YO10 5DD, U.K.
Elena BlagovaYork Structural Biology Laboratory, Department of Chemistry, The University of York, York YO10 5DD, U.K.
Jos ReijngoudMolecular Microbiology and Biotechnology, Institute of Biology Leiden, Leiden University, Sylviusweg 72, 2333 BE Leiden, The Netherlands.
Mark ArentshorstMolecular Microbiology and Biotechnology, Institute of Biology Leiden, Leiden University, Sylviusweg 72, 2333 BE Leiden, The Netherlands.
David OsbornNovozymes Inc., 1445 Drew Avenue, Davis, California 95618, United States.
Marc D MorantNovozymes A/S, Krogshøjvej 36, 2880 Bagsværd, Denmark.
Eric AbbateNovozymes Inc., 1445 Drew Avenue, Davis, California 95618, United States.
Mary A StringerNovozymes A/S, Krogshøjvej 36, 2880 Bagsværd, Denmark.
Kristian B R M KroghNovozymes A/S, Krogshøjvej 36, 2880 Bagsværd, Denmark.
Lluís RaichDepartament de Quımica Inorgànica i Orgànica (Secció de Química Orgànica) & Institut de Quimica Teòrica i Computacional (IQTCUB), Universitat de Barcelona, Martí i Franquès 1, 08028 Barcelona, Spain.
Carme RoviraDepartament de Quımica Inorgànica i Orgànica (Secció de Química Orgànica) & Institut de Quimica Teòrica i Computacional (IQTCUB), Universitat de Barcelona, Martí i Franquès 1, 08028 Barcelona, Spain.
Jean-Guy BerrinBiodiversité et Biotechnologie Fongiques (BBF), UMR1163, INRA, Aix Marseille University, F-13009 Marseille, France.
Gilles P van WezelMolecular Microbiology and Biotechnology, Institute of Biology Leiden, Leiden University, Sylviusweg 72, 2333 BE Leiden, The Netherlands.
Arthur F J RamMolecular Microbiology and Biotechnology, Institute of Biology Leiden, Leiden University, Sylviusweg 72, 2333 BE Leiden, The Netherlands.
Bogdan I FloreaLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA Leiden, The Netherlands.
Gijsbert A van der MarelLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA Leiden, The Netherlands.
Jeroen D C CodéeLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA Leiden, The Netherlands.
Keith S WilsonYork Structural Biology Laboratory, Department of Chemistry, The University of York, York YO10 5DD, U.K.
Liang WuYork Structural Biology Laboratory, Department of Chemistry, The University of York, York YO10 5DD, U.K.
Gideon J DaviesYork Structural Biology Laboratory, Department of Chemistry, The University of York, York YO10 5DD, U.K.
Herman S OverkleeftLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA Leiden, The Netherlands.
Leiden University · NLUniversity of York · GBNovozymes (Denmark) · DKNovozymes (United States) · USAix-Marseille Université · FRInstitució Catalana de Recerca i Estudis Avançats · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant polysaccharides represent a virtually unlimited feedstock for the generation of biofuels and other commodities. However, the extraordinary recalcitrance of plant polysaccharides toward breakdown necessitates a continued search for enzymes that degrade these materials efficiently under defined conditions. Activity-based protein profiling provides a route for the functional discovery of such enzymes in complex mixtures and under industrially relevant conditions. Here, we show the detection and identification of β-xylosidases and

Identifiers

PMID31263766
PMCPMC6598175
OpenAlexW2946054052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.